Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants
Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteris...
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2018
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oai:doaj.org-article:f15fa41a1567456bbadf5b59246f8cd72021-12-02T16:56:37ZBroad phylogenetic analysis of cation/proton antiporters reveals transport determinants10.1038/s41467-018-06770-52041-1723https://doaj.org/article/f15fa41a1567456bbadf5b59246f8cd72018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06770-5https://doaj.org/toc/2041-1723Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteristics.Gal MasratiManish DwivediAbraham RimonYael Gluck-MargolinAmit KesselHaim AshkenazyItay MayroseEtana PadanNir Ben-TalNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q Gal Masrati Manish Dwivedi Abraham Rimon Yael Gluck-Margolin Amit Kessel Haim Ashkenazy Itay Mayrose Etana Padan Nir Ben-Tal Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
| description |
Cation/proton antiporters (CPAs) play a major role in maintaining living cells’ homeostasis and are divided in two main groups: CPA1 and CPA2. Here authors use a comprehensive evolutionary analysis of 6537 representative CPAs and reveal a sequence motif that determines central phenotypic characteristics. |
| format |
article |
| author |
Gal Masrati Manish Dwivedi Abraham Rimon Yael Gluck-Margolin Amit Kessel Haim Ashkenazy Itay Mayrose Etana Padan Nir Ben-Tal |
| author_facet |
Gal Masrati Manish Dwivedi Abraham Rimon Yael Gluck-Margolin Amit Kessel Haim Ashkenazy Itay Mayrose Etana Padan Nir Ben-Tal |
| author_sort |
Gal Masrati |
| title |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
| title_short |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
| title_full |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
| title_fullStr |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
| title_full_unstemmed |
Broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
| title_sort |
broad phylogenetic analysis of cation/proton antiporters reveals transport determinants |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/f15fa41a1567456bbadf5b59246f8cd7 |
| work_keys_str_mv |
AT galmasrati broadphylogeneticanalysisofcationprotonantiportersrevealstransportdeterminants AT manishdwivedi broadphylogeneticanalysisofcationprotonantiportersrevealstransportdeterminants AT abrahamrimon broadphylogeneticanalysisofcationprotonantiportersrevealstransportdeterminants AT yaelgluckmargolin broadphylogeneticanalysisofcationprotonantiportersrevealstransportdeterminants AT amitkessel broadphylogeneticanalysisofcationprotonantiportersrevealstransportdeterminants AT haimashkenazy broadphylogeneticanalysisofcationprotonantiportersrevealstransportdeterminants AT itaymayrose broadphylogeneticanalysisofcationprotonantiportersrevealstransportdeterminants AT etanapadan broadphylogeneticanalysisofcationprotonantiportersrevealstransportdeterminants AT nirbental broadphylogeneticanalysisofcationprotonantiportersrevealstransportdeterminants |
| _version_ |
1718382775459905536 |