Human left ventral premotor cortex mediates matching of hand posture to object use.

Visuomotor transformations for grasping have been associated with a fronto-parietal network in the monkey brain. The human homologue of the parietal monkey region (AIP) has been identified as the anterior part of the intraparietal sulcus (aIPS), whereas the putative human equivalent of the monkey fr...

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Autores principales:	Guy Vingerhoets, Jo Nys, Pieterjan Honoré, Elisabeth Vandekerckhove, Pieter Vandemaele
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f1606a3b110b4657873ccc9cef446551
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spelling	oai:doaj.org-article:f1606a3b110b4657873ccc9cef4465512021-11-18T09:01:57ZHuman left ventral premotor cortex mediates matching of hand posture to object use.1932-620310.1371/journal.pone.0070480https://doaj.org/article/f1606a3b110b4657873ccc9cef4465512013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23936212/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Visuomotor transformations for grasping have been associated with a fronto-parietal network in the monkey brain. The human homologue of the parietal monkey region (AIP) has been identified as the anterior part of the intraparietal sulcus (aIPS), whereas the putative human equivalent of the monkey frontal region (F5) is located in the ventral part of the premotor cortex (vPMC). Results from animal studies suggest that monkey F5 is involved in the selection of appropriate hand postures relative to the constraints of the task. In humans, the functional roles of aIPS and vPMC appear to be more complex and the relative contribution of each region to grasp selection remains uncertain. The present study aimed to identify modulation in brain areas sensitive to the difficulty level of tool object - hand posture matching. Seventeen healthy right handed participants underwent fMRI while observing pictures of familiar tool objects followed by pictures of hand postures. The task was to decide whether the hand posture matched the functional use of the previously shown object. Conditions were manipulated for level of difficulty. Compared to a picture matching control task, the tool object - hand posture matching conditions conjointly showed increased modulation in several left hemispheric regions of the superior and inferior parietal lobules (including aIPS), the middle occipital gyrus, and the inferior temporal gyrus. Comparison of hard versus easy conditions selectively modulated the left inferior frontal gyrus with peak activity located in its opercular part (Brodmann area (BA) 44). We suggest that in the human brain, vPMC/BA44 is involved in the matching of hand posture configurations in accordance with visual and functional demands.Guy VingerhoetsJo NysPieterjan HonoréElisabeth VandekerckhovePieter VandemaelePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 7, p e70480 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Guy Vingerhoets Jo Nys Pieterjan Honoré Elisabeth Vandekerckhove Pieter Vandemaele Human left ventral premotor cortex mediates matching of hand posture to object use.
description	Visuomotor transformations for grasping have been associated with a fronto-parietal network in the monkey brain. The human homologue of the parietal monkey region (AIP) has been identified as the anterior part of the intraparietal sulcus (aIPS), whereas the putative human equivalent of the monkey frontal region (F5) is located in the ventral part of the premotor cortex (vPMC). Results from animal studies suggest that monkey F5 is involved in the selection of appropriate hand postures relative to the constraints of the task. In humans, the functional roles of aIPS and vPMC appear to be more complex and the relative contribution of each region to grasp selection remains uncertain. The present study aimed to identify modulation in brain areas sensitive to the difficulty level of tool object - hand posture matching. Seventeen healthy right handed participants underwent fMRI while observing pictures of familiar tool objects followed by pictures of hand postures. The task was to decide whether the hand posture matched the functional use of the previously shown object. Conditions were manipulated for level of difficulty. Compared to a picture matching control task, the tool object - hand posture matching conditions conjointly showed increased modulation in several left hemispheric regions of the superior and inferior parietal lobules (including aIPS), the middle occipital gyrus, and the inferior temporal gyrus. Comparison of hard versus easy conditions selectively modulated the left inferior frontal gyrus with peak activity located in its opercular part (Brodmann area (BA) 44). We suggest that in the human brain, vPMC/BA44 is involved in the matching of hand posture configurations in accordance with visual and functional demands.
format	article
author	Guy Vingerhoets Jo Nys Pieterjan Honoré Elisabeth Vandekerckhove Pieter Vandemaele
author_facet	Guy Vingerhoets Jo Nys Pieterjan Honoré Elisabeth Vandekerckhove Pieter Vandemaele
author_sort	Guy Vingerhoets
title	Human left ventral premotor cortex mediates matching of hand posture to object use.
title_short	Human left ventral premotor cortex mediates matching of hand posture to object use.
title_full	Human left ventral premotor cortex mediates matching of hand posture to object use.
title_fullStr	Human left ventral premotor cortex mediates matching of hand posture to object use.
title_full_unstemmed	Human left ventral premotor cortex mediates matching of hand posture to object use.
title_sort	human left ventral premotor cortex mediates matching of hand posture to object use.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/f1606a3b110b4657873ccc9cef446551
work_keys_str_mv	AT guyvingerhoets humanleftventralpremotorcortexmediatesmatchingofhandposturetoobjectuse AT jonys humanleftventralpremotorcortexmediatesmatchingofhandposturetoobjectuse AT pieterjanhonore humanleftventralpremotorcortexmediatesmatchingofhandposturetoobjectuse AT elisabethvandekerckhove humanleftventralpremotorcortexmediatesmatchingofhandposturetoobjectuse AT pietervandemaele humanleftventralpremotorcortexmediatesmatchingofhandposturetoobjectuse
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Human left ventral premotor cortex mediates matching of hand posture to object use.

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