Towards a data-integrated cell

Integration of omics data remains a challenge. Here, the authors introduce iCell, a framework to integrate tissue-specific protein–protein interaction, co-expression and genetic interaction data, enabling identification of the most rewired genes in cancer, unidentifiable in individual data layers.

Guardado en:

Detalles Bibliográficos
Autores principales:	Noël Malod-Dognin, Julia Petschnigg, Sam F. L. Windels, Janez Povh, Harry Hemingway, Robin Ketteler, Nataša Pržulj
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f16ba5ea82984765ad79c0f292ce025e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f16ba5ea82984765ad79c0f292ce025e
record_format	dspace
spelling	oai:doaj.org-article:f16ba5ea82984765ad79c0f292ce025e2021-12-02T16:57:50ZTowards a data-integrated cell10.1038/s41467-019-08797-82041-1723https://doaj.org/article/f16ba5ea82984765ad79c0f292ce025e2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08797-8https://doaj.org/toc/2041-1723Integration of omics data remains a challenge. Here, the authors introduce iCell, a framework to integrate tissue-specific protein–protein interaction, co-expression and genetic interaction data, enabling identification of the most rewired genes in cancer, unidentifiable in individual data layers.Noël Malod-DogninJulia PetschniggSam F. L. WindelsJanez PovhHarry HemingwayRobin KettelerNataša PržuljNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Noël Malod-Dognin Julia Petschnigg Sam F. L. Windels Janez Povh Harry Hemingway Robin Ketteler Nataša Pržulj Towards a data-integrated cell
description	Integration of omics data remains a challenge. Here, the authors introduce iCell, a framework to integrate tissue-specific protein–protein interaction, co-expression and genetic interaction data, enabling identification of the most rewired genes in cancer, unidentifiable in individual data layers.
format	article
author	Noël Malod-Dognin Julia Petschnigg Sam F. L. Windels Janez Povh Harry Hemingway Robin Ketteler Nataša Pržulj
author_facet	Noël Malod-Dognin Julia Petschnigg Sam F. L. Windels Janez Povh Harry Hemingway Robin Ketteler Nataša Pržulj
author_sort	Noël Malod-Dognin
title	Towards a data-integrated cell
title_short	Towards a data-integrated cell
title_full	Towards a data-integrated cell
title_fullStr	Towards a data-integrated cell
title_full_unstemmed	Towards a data-integrated cell
title_sort	towards a data-integrated cell
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/f16ba5ea82984765ad79c0f292ce025e
work_keys_str_mv	AT noelmaloddognin towardsadataintegratedcell AT juliapetschnigg towardsadataintegratedcell AT samflwindels towardsadataintegratedcell AT janezpovh towardsadataintegratedcell AT harryhemingway towardsadataintegratedcell AT robinketteler towardsadataintegratedcell AT natasaprzulj towardsadataintegratedcell
_version_	1718382482164809728

Towards a data-integrated cell

Ejemplares similares