An Unbound Proline-Rich Signaling Peptide Frequently Samples Cis Conformations in Gaussian Accelerated Molecular Dynamics Simulations

Disordered proline-rich motifs are common across the proteomes of many species and are often involved in protein-protein interactions. Proline is a unique amino acid due to the covalent bond between the backbone nitrogen and the proline side chain. The resulting five-membered ring allows proline to...

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Autores principales: Juan Alcantara, Robyn Stix, Katherine Huang, Acadia Connor, Ray East, Valeria Jaramillo-Martinez, Elliott J. Stollar, K. Aurelia Ball
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/f1791d82aafe4d9dbee25ef021463a37
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