Role of Growth Factors in the Adhesive Process in the Abdominal Cavity

Fibroproliferative diseases have been described in the lungs, kidneys, liver, eyes, heart, skin, and abdomen. Each fibrous pathology has causal factors and pathological manifestations characteristic of this organ and this condition. However, there are common mechanisms underlying many fibrous pathol...

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Autores principales:	N. N. Dremina, M. G. Shurygin, E. E. Chepurnikh, I. A. Shurygina
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2019
Materias:	adhesive disease growth factors connective tissue Science Q
Acceso en línea:	https://doaj.org/article/f17ed8bba16649b69d2af8a4eada2e65
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spelling	oai:doaj.org-article:f17ed8bba16649b69d2af8a4eada2e652021-11-23T06:14:43ZRole of Growth Factors in the Adhesive Process in the Abdominal Cavity2541-94202587-959610.29413/ABS.2019-4.5.16https://doaj.org/article/f17ed8bba16649b69d2af8a4eada2e652019-11-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2177https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Fibroproliferative diseases have been described in the lungs, kidneys, liver, eyes, heart, skin, and abdomen. Each fibrous pathology has causal factors and pathological manifestations characteristic of this organ and this condition. However, there are common mechanisms underlying many fibrous pathologies. This gives potential value to studies focused on specific processes, among which is the adhesive process in the abdominal cavity. The study of growth factors in the formation of connective tissue contributes to a better understanding of the pathogenetic picture in this pathology. It is shown that vascular endothelial growth factor, fibroblast growth factor, transforming growth factor, platelet growth factor, insulin-like growth factor and keratinocyte growth factor participate in the development of abdominal adhesions. Each of these factors contributes significantly to the formation of peritoneal fibrosis.Thus, damage to any tissue initiates a complex multistage process, which is regulated by a large number of cytokines and growth factors. Growth factors control cell migration, proliferation, differentiation, and survival. In addition, they are able to influence the expression of other factors involved in the regenerative response. Understanding the process that develops during the formation of the adhesive process in the abdominal cavity and the growth factors affecting it is important for their further use in order to prevent the pathological process.N. N. DreminaM. G. ShuryginE. E. ChepurnikhI. A. ShuryginaScientific Сentre for Family Health and Human Reproduction Problemsarticleadhesive diseasegrowth factorsconnective tissueScienceQRUActa Biomedica Scientifica, Vol 4, Iss 5, Pp 98-103 (2019)
institution	DOAJ
collection	DOAJ
language	RU
topic	adhesive disease growth factors connective tissue Science Q
spellingShingle	adhesive disease growth factors connective tissue Science Q N. N. Dremina M. G. Shurygin E. E. Chepurnikh I. A. Shurygina Role of Growth Factors in the Adhesive Process in the Abdominal Cavity
description	Fibroproliferative diseases have been described in the lungs, kidneys, liver, eyes, heart, skin, and abdomen. Each fibrous pathology has causal factors and pathological manifestations characteristic of this organ and this condition. However, there are common mechanisms underlying many fibrous pathologies. This gives potential value to studies focused on specific processes, among which is the adhesive process in the abdominal cavity. The study of growth factors in the formation of connective tissue contributes to a better understanding of the pathogenetic picture in this pathology. It is shown that vascular endothelial growth factor, fibroblast growth factor, transforming growth factor, platelet growth factor, insulin-like growth factor and keratinocyte growth factor participate in the development of abdominal adhesions. Each of these factors contributes significantly to the formation of peritoneal fibrosis.Thus, damage to any tissue initiates a complex multistage process, which is regulated by a large number of cytokines and growth factors. Growth factors control cell migration, proliferation, differentiation, and survival. In addition, they are able to influence the expression of other factors involved in the regenerative response. Understanding the process that develops during the formation of the adhesive process in the abdominal cavity and the growth factors affecting it is important for their further use in order to prevent the pathological process.
format	article
author	N. N. Dremina M. G. Shurygin E. E. Chepurnikh I. A. Shurygina
author_facet	N. N. Dremina M. G. Shurygin E. E. Chepurnikh I. A. Shurygina
author_sort	N. N. Dremina
title	Role of Growth Factors in the Adhesive Process in the Abdominal Cavity
title_short	Role of Growth Factors in the Adhesive Process in the Abdominal Cavity
title_full	Role of Growth Factors in the Adhesive Process in the Abdominal Cavity
title_fullStr	Role of Growth Factors in the Adhesive Process in the Abdominal Cavity
title_full_unstemmed	Role of Growth Factors in the Adhesive Process in the Abdominal Cavity
title_sort	role of growth factors in the adhesive process in the abdominal cavity
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2019
url	https://doaj.org/article/f17ed8bba16649b69d2af8a4eada2e65
work_keys_str_mv	AT nndremina roleofgrowthfactorsintheadhesiveprocessintheabdominalcavity AT mgshurygin roleofgrowthfactorsintheadhesiveprocessintheabdominalcavity AT eechepurnikh roleofgrowthfactorsintheadhesiveprocessintheabdominalcavity AT iashurygina roleofgrowthfactorsintheadhesiveprocessintheabdominalcavity
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Role of Growth Factors in the Adhesive Process in the Abdominal Cavity

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