Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis

The growth of lymph nodes in response to infection requires lymphangiogenesis. Dubey et al. show that the mesenteric lymph node lymphangiogenesis upon helminth infection depends on the signaling loop between the B and fibroblastic reticular cells (FRCs), whereby the FRCs respond to lymphotoxin secre...

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Autores principales: Lalit Kumar Dubey, Praneeth Karempudi, Sanjiv A. Luther, Burkhard Ludewig, Nicola L. Harris
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f18207b2fff04d98b567b391fa0c5d37
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spelling oai:doaj.org-article:f18207b2fff04d98b567b391fa0c5d372021-12-02T14:42:19ZInteractions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis10.1038/s41467-017-00504-92041-1723https://doaj.org/article/f18207b2fff04d98b567b391fa0c5d372017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00504-9https://doaj.org/toc/2041-1723The growth of lymph nodes in response to infection requires lymphangiogenesis. Dubey et al. show that the mesenteric lymph node lymphangiogenesis upon helminth infection depends on the signaling loop between the B and fibroblastic reticular cells (FRCs), whereby the FRCs respond to lymphotoxin secreted by B cells by releasing B cell activating factor.Lalit Kumar DubeyPraneeth KarempudiSanjiv A. LutherBurkhard LudewigNicola L. HarrisNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lalit Kumar Dubey
Praneeth Karempudi
Sanjiv A. Luther
Burkhard Ludewig
Nicola L. Harris
Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
description The growth of lymph nodes in response to infection requires lymphangiogenesis. Dubey et al. show that the mesenteric lymph node lymphangiogenesis upon helminth infection depends on the signaling loop between the B and fibroblastic reticular cells (FRCs), whereby the FRCs respond to lymphotoxin secreted by B cells by releasing B cell activating factor.
format article
author Lalit Kumar Dubey
Praneeth Karempudi
Sanjiv A. Luther
Burkhard Ludewig
Nicola L. Harris
author_facet Lalit Kumar Dubey
Praneeth Karempudi
Sanjiv A. Luther
Burkhard Ludewig
Nicola L. Harris
author_sort Lalit Kumar Dubey
title Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
title_short Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
title_full Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
title_fullStr Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
title_full_unstemmed Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
title_sort interactions between fibroblastic reticular cells and b cells promote mesenteric lymph node lymphangiogenesis
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/f18207b2fff04d98b567b391fa0c5d37
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