Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
The growth of lymph nodes in response to infection requires lymphangiogenesis. Dubey et al. show that the mesenteric lymph node lymphangiogenesis upon helminth infection depends on the signaling loop between the B and fibroblastic reticular cells (FRCs), whereby the FRCs respond to lymphotoxin secre...
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Nature Portfolio
2017
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oai:doaj.org-article:f18207b2fff04d98b567b391fa0c5d372021-12-02T14:42:19ZInteractions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis10.1038/s41467-017-00504-92041-1723https://doaj.org/article/f18207b2fff04d98b567b391fa0c5d372017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00504-9https://doaj.org/toc/2041-1723The growth of lymph nodes in response to infection requires lymphangiogenesis. Dubey et al. show that the mesenteric lymph node lymphangiogenesis upon helminth infection depends on the signaling loop between the B and fibroblastic reticular cells (FRCs), whereby the FRCs respond to lymphotoxin secreted by B cells by releasing B cell activating factor.Lalit Kumar DubeyPraneeth KarempudiSanjiv A. LutherBurkhard LudewigNicola L. HarrisNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q Lalit Kumar Dubey Praneeth Karempudi Sanjiv A. Luther Burkhard Ludewig Nicola L. Harris Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis |
description |
The growth of lymph nodes in response to infection requires lymphangiogenesis. Dubey et al. show that the mesenteric lymph node lymphangiogenesis upon helminth infection depends on the signaling loop between the B and fibroblastic reticular cells (FRCs), whereby the FRCs respond to lymphotoxin secreted by B cells by releasing B cell activating factor. |
format |
article |
author |
Lalit Kumar Dubey Praneeth Karempudi Sanjiv A. Luther Burkhard Ludewig Nicola L. Harris |
author_facet |
Lalit Kumar Dubey Praneeth Karempudi Sanjiv A. Luther Burkhard Ludewig Nicola L. Harris |
author_sort |
Lalit Kumar Dubey |
title |
Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis |
title_short |
Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis |
title_full |
Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis |
title_fullStr |
Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis |
title_full_unstemmed |
Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis |
title_sort |
interactions between fibroblastic reticular cells and b cells promote mesenteric lymph node lymphangiogenesis |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/f18207b2fff04d98b567b391fa0c5d37 |
work_keys_str_mv |
AT lalitkumardubey interactionsbetweenfibroblasticreticularcellsandbcellspromotemesentericlymphnodelymphangiogenesis AT praneethkarempudi interactionsbetweenfibroblasticreticularcellsandbcellspromotemesentericlymphnodelymphangiogenesis AT sanjivaluther interactionsbetweenfibroblasticreticularcellsandbcellspromotemesentericlymphnodelymphangiogenesis AT burkhardludewig interactionsbetweenfibroblasticreticularcellsandbcellspromotemesentericlymphnodelymphangiogenesis AT nicolalharris interactionsbetweenfibroblasticreticularcellsandbcellspromotemesentericlymphnodelymphangiogenesis |
_version_ |
1718389725611425792 |