SAM-VI riboswitch structure and signature for ligand discrimination

Riboswitches are conserved RNA domains located in the non-coding region of mRNA that recognize cellular metabolites and, in turn, regulate gene expression. Here the authors report the structure of the recently identified SAM-VI riboswitch and provide insight into its mechanism of ligand discriminati...

Full description

Saved in:
Bibliographic Details
Main Authors: Aiai Sun, Catherina Gasser, Fudong Li, Hao Chen, Stefan Mair, Olga Krasheninina, Ronald Micura, Aiming Ren
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/f18643b7ff2249109a5ed2bb1fb4bbbb
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Riboswitches are conserved RNA domains located in the non-coding region of mRNA that recognize cellular metabolites and, in turn, regulate gene expression. Here the authors report the structure of the recently identified SAM-VI riboswitch and provide insight into its mechanism of ligand discrimination.