SAM-VI riboswitch structure and signature for ligand discrimination

Riboswitches are conserved RNA domains located in the non-coding region of mRNA that recognize cellular metabolites and, in turn, regulate gene expression. Here the authors report the structure of the recently identified SAM-VI riboswitch and provide insight into its mechanism of ligand discriminati...

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Autores principales: Aiai Sun, Catherina Gasser, Fudong Li, Hao Chen, Stefan Mair, Olga Krasheninina, Ronald Micura, Aiming Ren
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f18643b7ff2249109a5ed2bb1fb4bbbb
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spelling oai:doaj.org-article:f18643b7ff2249109a5ed2bb1fb4bbbb2021-12-02T17:01:46ZSAM-VI riboswitch structure and signature for ligand discrimination10.1038/s41467-019-13600-92041-1723https://doaj.org/article/f18643b7ff2249109a5ed2bb1fb4bbbb2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13600-9https://doaj.org/toc/2041-1723Riboswitches are conserved RNA domains located in the non-coding region of mRNA that recognize cellular metabolites and, in turn, regulate gene expression. Here the authors report the structure of the recently identified SAM-VI riboswitch and provide insight into its mechanism of ligand discrimination.Aiai SunCatherina GasserFudong LiHao ChenStefan MairOlga KrashenininaRonald MicuraAiming RenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aiai Sun
Catherina Gasser
Fudong Li
Hao Chen
Stefan Mair
Olga Krasheninina
Ronald Micura
Aiming Ren
SAM-VI riboswitch structure and signature for ligand discrimination
description Riboswitches are conserved RNA domains located in the non-coding region of mRNA that recognize cellular metabolites and, in turn, regulate gene expression. Here the authors report the structure of the recently identified SAM-VI riboswitch and provide insight into its mechanism of ligand discrimination.
format article
author Aiai Sun
Catherina Gasser
Fudong Li
Hao Chen
Stefan Mair
Olga Krasheninina
Ronald Micura
Aiming Ren
author_facet Aiai Sun
Catherina Gasser
Fudong Li
Hao Chen
Stefan Mair
Olga Krasheninina
Ronald Micura
Aiming Ren
author_sort Aiai Sun
title SAM-VI riboswitch structure and signature for ligand discrimination
title_short SAM-VI riboswitch structure and signature for ligand discrimination
title_full SAM-VI riboswitch structure and signature for ligand discrimination
title_fullStr SAM-VI riboswitch structure and signature for ligand discrimination
title_full_unstemmed SAM-VI riboswitch structure and signature for ligand discrimination
title_sort sam-vi riboswitch structure and signature for ligand discrimination
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/f18643b7ff2249109a5ed2bb1fb4bbbb
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