Isolation of reovirus T3D mutants capable of infecting human tumor cells independent of junction adhesion molecule-A.
Mammalian Reovirus is a double-stranded RNA virus with a distinctive preference to replicate in and lyse transformed cells. On that account, Reovirus type 3 Dearing (T3D) is clinically evaluated as oncolytic agent. The therapeutic efficacy of this approach depends in part on the accessibility of the...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2012
|
| Subjects: | |
| Online Access: | https://doaj.org/article/f188a33e083a4395bb834fe1fedf0c5c |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!