Isolation of reovirus T3D mutants capable of infecting human tumor cells independent of junction adhesion molecule-A.
Mammalian Reovirus is a double-stranded RNA virus with a distinctive preference to replicate in and lyse transformed cells. On that account, Reovirus type 3 Dearing (T3D) is clinically evaluated as oncolytic agent. The therapeutic efficacy of this approach depends in part on the accessibility of the...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2012
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/f188a33e083a4395bb834fe1fedf0c5c |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|