Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes
Ribosomes assemble through the hierarchical addition of proteins to a ribosomal RNA scaffold. Here the authors use three-color single-molecule FRET to show how the dynamics of the rRNA dictate the order in which multiple proteins assemble on the 5′ domain of the E. coli 16S rRNA.
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Autores principales: | Sanjaya C. Abeysirigunawardena, Hajin Kim, Jonathan Lai, Kaushik Ragunathan, Mollie C. Rappé, Zaida Luthey-Schulten, Taekjip Ha, Sarah A. Woodson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/f192a5c8e0dd4953a26b536e8ef4f6f9 |
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