Natural selection favoring more transmissible HIV detected in United States molecular transmission network

Here, the authors use a molecular epidemiological approach to investigate the frequency and intensity of clustering of HIV with different set-point viral loads and find that frequently transmitted strains in genetic transmission clusters have significantly higher viral loads than nonclustered viruse...

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Autores principales: Joel O. Wertheim, Alexandra M. Oster, William M. Switzer, Chenhua Zhang, Nivedha Panneer, Ellsworth Campbell, Neeraja Saduvala, Jeffrey A. Johnson, Walid Heneine
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f197174031d34c87aa739dd453d9ef55
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Sumario:Here, the authors use a molecular epidemiological approach to investigate the frequency and intensity of clustering of HIV with different set-point viral loads and find that frequently transmitted strains in genetic transmission clusters have significantly higher viral loads than nonclustered viruses.