Natural selection favoring more transmissible HIV detected in United States molecular transmission network

Here, the authors use a molecular epidemiological approach to investigate the frequency and intensity of clustering of HIV with different set-point viral loads and find that frequently transmitted strains in genetic transmission clusters have significantly higher viral loads than nonclustered viruse...

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Autores principales: Joel O. Wertheim, Alexandra M. Oster, William M. Switzer, Chenhua Zhang, Nivedha Panneer, Ellsworth Campbell, Neeraja Saduvala, Jeffrey A. Johnson, Walid Heneine
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f197174031d34c87aa739dd453d9ef55
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spelling oai:doaj.org-article:f197174031d34c87aa739dd453d9ef552021-12-02T16:57:21ZNatural selection favoring more transmissible HIV detected in United States molecular transmission network10.1038/s41467-019-13723-z2041-1723https://doaj.org/article/f197174031d34c87aa739dd453d9ef552019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13723-zhttps://doaj.org/toc/2041-1723Here, the authors use a molecular epidemiological approach to investigate the frequency and intensity of clustering of HIV with different set-point viral loads and find that frequently transmitted strains in genetic transmission clusters have significantly higher viral loads than nonclustered viruses.Joel O. WertheimAlexandra M. OsterWilliam M. SwitzerChenhua ZhangNivedha PanneerEllsworth CampbellNeeraja SaduvalaJeffrey A. JohnsonWalid HeneineNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Joel O. Wertheim
Alexandra M. Oster
William M. Switzer
Chenhua Zhang
Nivedha Panneer
Ellsworth Campbell
Neeraja Saduvala
Jeffrey A. Johnson
Walid Heneine
Natural selection favoring more transmissible HIV detected in United States molecular transmission network
description Here, the authors use a molecular epidemiological approach to investigate the frequency and intensity of clustering of HIV with different set-point viral loads and find that frequently transmitted strains in genetic transmission clusters have significantly higher viral loads than nonclustered viruses.
format article
author Joel O. Wertheim
Alexandra M. Oster
William M. Switzer
Chenhua Zhang
Nivedha Panneer
Ellsworth Campbell
Neeraja Saduvala
Jeffrey A. Johnson
Walid Heneine
author_facet Joel O. Wertheim
Alexandra M. Oster
William M. Switzer
Chenhua Zhang
Nivedha Panneer
Ellsworth Campbell
Neeraja Saduvala
Jeffrey A. Johnson
Walid Heneine
author_sort Joel O. Wertheim
title Natural selection favoring more transmissible HIV detected in United States molecular transmission network
title_short Natural selection favoring more transmissible HIV detected in United States molecular transmission network
title_full Natural selection favoring more transmissible HIV detected in United States molecular transmission network
title_fullStr Natural selection favoring more transmissible HIV detected in United States molecular transmission network
title_full_unstemmed Natural selection favoring more transmissible HIV detected in United States molecular transmission network
title_sort natural selection favoring more transmissible hiv detected in united states molecular transmission network
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/f197174031d34c87aa739dd453d9ef55
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