Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution

Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution

Nasopharyngeal carcinoma is a diverse cancer characterised by a heterogeneous microenvironment. Here, the authors use single cell sequencing to analyse the tumour microenvironment in 10 nasopharyngeal carcinoma tumours and identify different cell types including immune-suppressive T regulatory, tole...

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Autores principales: Yang Liu, Shuai He, Xi-Liang Wang, Wan Peng, Qiu-Yan Chen, Dong-Mei Chi, Jie-Rong Chen, Bo-Wei Han, Guo-Wang Lin, Yi-Qi Li, Qian-Yu Wang, Rou-Jun Peng, Pan-Pan Wei, Xiang Guo, Bo Li, Xiaojun Xia, Hai-Qiang Mai, Xue-Da Hu, Zemin Zhang, Yi-Xin Zeng, Jin-Xin Bei
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f1978be2a763451db9da5aca4be70f2e
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spelling oai:doaj.org-article:f1978be2a763451db9da5aca4be70f2e2021-12-02T14:06:09ZTumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution10.1038/s41467-021-21043-42041-1723https://doaj.org/article/f1978be2a763451db9da5aca4be70f2e2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21043-4https://doaj.org/toc/2041-1723Nasopharyngeal carcinoma is a diverse cancer characterised by a heterogeneous microenvironment. Here, the authors use single cell sequencing to analyse the tumour microenvironment in 10 nasopharyngeal carcinoma tumours and identify different cell types including immune-suppressive T regulatory, tolerogenic dendritic, and exhausted CD8 T cells.Yang LiuShuai HeXi-Liang WangWan PengQiu-Yan ChenDong-Mei ChiJie-Rong ChenBo-Wei HanGuo-Wang LinYi-Qi LiQian-Yu WangRou-Jun PengPan-Pan WeiXiang GuoBo LiXiaojun XiaHai-Qiang MaiXue-Da HuZemin ZhangYi-Xin ZengJin-Xin BeiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yang Liu
Shuai He
Xi-Liang Wang
Wan Peng
Qiu-Yan Chen
Dong-Mei Chi
Jie-Rong Chen
Bo-Wei Han
Guo-Wang Lin
Yi-Qi Li
Qian-Yu Wang
Rou-Jun Peng
Pan-Pan Wei
Xiang Guo
Bo Li
Xiaojun Xia
Hai-Qiang Mai
Xue-Da Hu
Zemin Zhang
Yi-Xin Zeng
Jin-Xin Bei
Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution
description Nasopharyngeal carcinoma is a diverse cancer characterised by a heterogeneous microenvironment. Here, the authors use single cell sequencing to analyse the tumour microenvironment in 10 nasopharyngeal carcinoma tumours and identify different cell types including immune-suppressive T regulatory, tolerogenic dendritic, and exhausted CD8 T cells.
format article
author Yang Liu
Shuai He
Xi-Liang Wang
Wan Peng
Qiu-Yan Chen
Dong-Mei Chi
Jie-Rong Chen
Bo-Wei Han
Guo-Wang Lin
Yi-Qi Li
Qian-Yu Wang
Rou-Jun Peng
Pan-Pan Wei
Xiang Guo
Bo Li
Xiaojun Xia
Hai-Qiang Mai
Xue-Da Hu
Zemin Zhang
Yi-Xin Zeng
Jin-Xin Bei
author_facet Yang Liu
Shuai He
Xi-Liang Wang
Wan Peng
Qiu-Yan Chen
Dong-Mei Chi
Jie-Rong Chen
Bo-Wei Han
Guo-Wang Lin
Yi-Qi Li
Qian-Yu Wang
Rou-Jun Peng
Pan-Pan Wei
Xiang Guo
Bo Li
Xiaojun Xia
Hai-Qiang Mai
Xue-Da Hu
Zemin Zhang
Yi-Xin Zeng
Jin-Xin Bei
author_sort Yang Liu
title Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution
title_short Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution
title_full Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution
title_fullStr Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution
title_full_unstemmed Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution
title_sort tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f1978be2a763451db9da5aca4be70f2e
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