Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform

Extracellular vesicles (EVs) influence host-pathogen interactions, but EV biogenesis in gram-positive bacteria remains elusive. Here authors characterize EVs from Staphylococcus aureus and show that phenol-soluble modulins and autolysins promote EV biogenesis by disrupting the membrane and cell wall...

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Autores principales:	Xiaogang Wang, Christopher D. Thompson, Christopher Weidenmaier, Jean C. Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f19b7be7eb15436384641271771b100d
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spelling	oai:doaj.org-article:f19b7be7eb15436384641271771b100d2021-12-02T16:50:07ZRelease of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform10.1038/s41467-018-03847-z2041-1723https://doaj.org/article/f19b7be7eb15436384641271771b100d2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03847-zhttps://doaj.org/toc/2041-1723Extracellular vesicles (EVs) influence host-pathogen interactions, but EV biogenesis in gram-positive bacteria remains elusive. Here authors characterize EVs from Staphylococcus aureus and show that phenol-soluble modulins and autolysins promote EV biogenesis by disrupting the membrane and cell wall.Xiaogang WangChristopher D. ThompsonChristopher WeidenmaierJean C. LeeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaogang Wang Christopher D. Thompson Christopher Weidenmaier Jean C. Lee Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform
description	Extracellular vesicles (EVs) influence host-pathogen interactions, but EV biogenesis in gram-positive bacteria remains elusive. Here authors characterize EVs from Staphylococcus aureus and show that phenol-soluble modulins and autolysins promote EV biogenesis by disrupting the membrane and cell wall.
format	article
author	Xiaogang Wang Christopher D. Thompson Christopher Weidenmaier Jean C. Lee
author_facet	Xiaogang Wang Christopher D. Thompson Christopher Weidenmaier Jean C. Lee
author_sort	Xiaogang Wang
title	Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform
title_short	Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform
title_full	Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform
title_fullStr	Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform
title_full_unstemmed	Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform
title_sort	release of staphylococcus aureus extracellular vesicles and their application as a vaccine platform
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f19b7be7eb15436384641271771b100d
work_keys_str_mv	AT xiaogangwang releaseofstaphylococcusaureusextracellularvesiclesandtheirapplicationasavaccineplatform AT christopherdthompson releaseofstaphylococcusaureusextracellularvesiclesandtheirapplicationasavaccineplatform AT christopherweidenmaier releaseofstaphylococcusaureusextracellularvesiclesandtheirapplicationasavaccineplatform AT jeanclee releaseofstaphylococcusaureusextracellularvesiclesandtheirapplicationasavaccineplatform
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Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform

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