Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania

Rheumatic heart disease (RHD) is a chronic auto-inflammatory reaction to group A streptococcal infection, and frequently occurs in individuals from the South Pacific. This study finds a novel association between an immunoglobulin heavy chain allele and risk of RHD in Pacific Islanders and South Asia...

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Autores principales: Tom Parks, Mariana M. Mirabel, Joseph Kado, Kathryn Auckland, Jaroslaw Nowak, Anna Rautanen, Alexander J. Mentzer, Eloi Marijon, Xavier Jouven, Mai Ling Perman, Tuliana Cua, John K. Kauwe, John B. Allen, Henry Taylor, Kathryn J. Robson, Charlotte M. Deane, Andrew C. Steer, Adrian V. S. Hill, Pacific Islands Rheumatic Heart Disease Genetics Network
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f1a3562bc39247d39047f5629a43276b
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spelling oai:doaj.org-article:f1a3562bc39247d39047f5629a43276b2021-12-02T15:39:06ZAssociation between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania10.1038/ncomms149462041-1723https://doaj.org/article/f1a3562bc39247d39047f5629a43276b2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms14946https://doaj.org/toc/2041-1723Rheumatic heart disease (RHD) is a chronic auto-inflammatory reaction to group A streptococcal infection, and frequently occurs in individuals from the South Pacific. This study finds a novel association between an immunoglobulin heavy chain allele and risk of RHD in Pacific Islanders and South Asians.Tom ParksMariana M. MirabelJoseph KadoKathryn AucklandJaroslaw NowakAnna RautanenAlexander J. MentzerEloi MarijonXavier JouvenMai Ling PermanTuliana CuaJohn K. KauweJohn B. AllenHenry TaylorKathryn J. RobsonCharlotte M. DeaneAndrew C. SteerAdrian V. S. HillPacific Islands Rheumatic Heart Disease Genetics NetworkNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Tom Parks
Mariana M. Mirabel
Joseph Kado
Kathryn Auckland
Jaroslaw Nowak
Anna Rautanen
Alexander J. Mentzer
Eloi Marijon
Xavier Jouven
Mai Ling Perman
Tuliana Cua
John K. Kauwe
John B. Allen
Henry Taylor
Kathryn J. Robson
Charlotte M. Deane
Andrew C. Steer
Adrian V. S. Hill
Pacific Islands Rheumatic Heart Disease Genetics Network
Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania
description Rheumatic heart disease (RHD) is a chronic auto-inflammatory reaction to group A streptococcal infection, and frequently occurs in individuals from the South Pacific. This study finds a novel association between an immunoglobulin heavy chain allele and risk of RHD in Pacific Islanders and South Asians.
format article
author Tom Parks
Mariana M. Mirabel
Joseph Kado
Kathryn Auckland
Jaroslaw Nowak
Anna Rautanen
Alexander J. Mentzer
Eloi Marijon
Xavier Jouven
Mai Ling Perman
Tuliana Cua
John K. Kauwe
John B. Allen
Henry Taylor
Kathryn J. Robson
Charlotte M. Deane
Andrew C. Steer
Adrian V. S. Hill
Pacific Islands Rheumatic Heart Disease Genetics Network
author_facet Tom Parks
Mariana M. Mirabel
Joseph Kado
Kathryn Auckland
Jaroslaw Nowak
Anna Rautanen
Alexander J. Mentzer
Eloi Marijon
Xavier Jouven
Mai Ling Perman
Tuliana Cua
John K. Kauwe
John B. Allen
Henry Taylor
Kathryn J. Robson
Charlotte M. Deane
Andrew C. Steer
Adrian V. S. Hill
Pacific Islands Rheumatic Heart Disease Genetics Network
author_sort Tom Parks
title Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania
title_short Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania
title_full Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania
title_fullStr Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania
title_full_unstemmed Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania
title_sort association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in oceania
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/f1a3562bc39247d39047f5629a43276b
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