Immunomagnetic nanoparticle-based assays for detection of biomarkers

Hoyoung Park,1,2 Mintai P Hwang,1 Kwan Hyi Lee1,2 1Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, 2Department of Biomedical Engineering, University of Science and Technology, Seoul, Republic of Korea Abstract: The emergence of biomarkers as key pla...

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Autores principales:	Park H, Hwang MP, Lee KH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/f1a75ee3ec954c10899fd6933b79fc83
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spelling	oai:doaj.org-article:f1a75ee3ec954c10899fd6933b79fc832021-12-02T02:11:17ZImmunomagnetic nanoparticle-based assays for detection of biomarkers1176-91141178-2013https://doaj.org/article/f1a75ee3ec954c10899fd6933b79fc832013-11-01T00:00:00Zhttp://www.dovepress.com/immunomagnetic-nanoparticle-based-assays-for-detection-of-biomarkers-a15061https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Hoyoung Park,1,2 Mintai P Hwang,1 Kwan Hyi Lee1,2 1Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, 2Department of Biomedical Engineering, University of Science and Technology, Seoul, Republic of Korea Abstract: The emergence of biomarkers as key players in the paradigm shift towards preventative medicine underscores the need for their detection and quantification. Advances made in the field of nanotechnology have played a crucial role in achieving these needs, and have contributed to recent advances in the field of medicine. Nanoparticle-based immunomagnetic assays, in particular, offer numerous advantages that utilize the unique physical properties of magnetic nanoparticles. In this review, we focus on recent developments and trends with regards to immunomagnetic assays used for detection of biomarkers. The various immunomagnetic assays are categorized into the following: particle-based multiplexing, signal control, microfluidics, microarray, and automation. Herein, we analyze each category and discuss their advantages and disadvantages. Keywords: magnetic, multiplex, signal control, microfluidics, microarrays, automationPark HHwang MPLee KHDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2013, Iss Issue 1, Pp 4543-4552 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Park H Hwang MP Lee KH Immunomagnetic nanoparticle-based assays for detection of biomarkers
description	Hoyoung Park,1,2 Mintai P Hwang,1 Kwan Hyi Lee1,2 1Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, 2Department of Biomedical Engineering, University of Science and Technology, Seoul, Republic of Korea Abstract: The emergence of biomarkers as key players in the paradigm shift towards preventative medicine underscores the need for their detection and quantification. Advances made in the field of nanotechnology have played a crucial role in achieving these needs, and have contributed to recent advances in the field of medicine. Nanoparticle-based immunomagnetic assays, in particular, offer numerous advantages that utilize the unique physical properties of magnetic nanoparticles. In this review, we focus on recent developments and trends with regards to immunomagnetic assays used for detection of biomarkers. The various immunomagnetic assays are categorized into the following: particle-based multiplexing, signal control, microfluidics, microarray, and automation. Herein, we analyze each category and discuss their advantages and disadvantages. Keywords: magnetic, multiplex, signal control, microfluidics, microarrays, automation
format	article
author	Park H Hwang MP Lee KH
author_facet	Park H Hwang MP Lee KH
author_sort	Park H
title	Immunomagnetic nanoparticle-based assays for detection of biomarkers
title_short	Immunomagnetic nanoparticle-based assays for detection of biomarkers
title_full	Immunomagnetic nanoparticle-based assays for detection of biomarkers
title_fullStr	Immunomagnetic nanoparticle-based assays for detection of biomarkers
title_full_unstemmed	Immunomagnetic nanoparticle-based assays for detection of biomarkers
title_sort	immunomagnetic nanoparticle-based assays for detection of biomarkers
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/f1a75ee3ec954c10899fd6933b79fc83
work_keys_str_mv	AT parkh immunomagneticnanoparticlebasedassaysfordetectionofbiomarkers AT hwangmp immunomagneticnanoparticlebasedassaysfordetectionofbiomarkers AT leekh immunomagneticnanoparticlebasedassaysfordetectionofbiomarkers
_version_	1718402686758420480

Immunomagnetic nanoparticle-based assays for detection of biomarkers

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