Multiple stages of evolutionary change in anthrax toxin receptor expression in humans

Animal husbandry and hunting has increased human exposure to pathogens. Here, the authors investigate the evolution of human host gene expression to Bacillus anthracis infection, the bacterium that causes anthrax disease. They observe recent positive selection, suggestive of human genome adaptation...

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Autores principales:	Lauren A. Choate, Gilad Barshad, Pierce W. McMahon, Iskander Said, Edward J. Rice, Paul R. Munn, James J. Lewis, Charles G. Danko
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f1abda7d72c149088dee837f05360067
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spelling	oai:doaj.org-article:f1abda7d72c149088dee837f053600672021-11-21T12:34:39ZMultiple stages of evolutionary change in anthrax toxin receptor expression in humans10.1038/s41467-021-26854-z2041-1723https://doaj.org/article/f1abda7d72c149088dee837f053600672021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26854-zhttps://doaj.org/toc/2041-1723Animal husbandry and hunting has increased human exposure to pathogens. Here, the authors investigate the evolution of human host gene expression to Bacillus anthracis infection, the bacterium that causes anthrax disease. They observe recent positive selection, suggestive of human genome adaptation to anthrax disease.Lauren A. ChoateGilad BarshadPierce W. McMahonIskander SaidEdward J. RicePaul R. MunnJames J. LewisCharles G. DankoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lauren A. Choate Gilad Barshad Pierce W. McMahon Iskander Said Edward J. Rice Paul R. Munn James J. Lewis Charles G. Danko Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
description	Animal husbandry and hunting has increased human exposure to pathogens. Here, the authors investigate the evolution of human host gene expression to Bacillus anthracis infection, the bacterium that causes anthrax disease. They observe recent positive selection, suggestive of human genome adaptation to anthrax disease.
format	article
author	Lauren A. Choate Gilad Barshad Pierce W. McMahon Iskander Said Edward J. Rice Paul R. Munn James J. Lewis Charles G. Danko
author_facet	Lauren A. Choate Gilad Barshad Pierce W. McMahon Iskander Said Edward J. Rice Paul R. Munn James J. Lewis Charles G. Danko
author_sort	Lauren A. Choate
title	Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
title_short	Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
title_full	Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
title_fullStr	Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
title_full_unstemmed	Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
title_sort	multiple stages of evolutionary change in anthrax toxin receptor expression in humans
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f1abda7d72c149088dee837f05360067
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Multiple stages of evolutionary change in anthrax toxin receptor expression in humans

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