Cognitive function and 10 year mortality in an 85 year-old community-dwelling population

Yutaka Takata,1 Toshihiro Ansai,2 Inho Soh,2 Shuji Awano,2 Ikuo Nakamichi,1 Sumio Akifusa,3 Kenichi Goto,1 Akihiro Yoshida,2 Hiroki Fujii,1 Ritsuko Fujisawa,1 Kazuo Sonoki31Division of General Internal Medicine, Kyushu Dental University, 2Division of Community Oral Health Development, Kyushu Dental...

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Autores principales:	Takata Y, Ansai T, Soh I, Awano S, Nakamichi I, Akifusa S, Goto K, Yoshida A, Fujii H, Fujisawa R, Sonoki K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	cognition elderly mortality community-dwelling MMSE Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/f1b1527ae77e4784819fd836dbb60dd2
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spelling	oai:doaj.org-article:f1b1527ae77e4784819fd836dbb60dd22021-12-02T01:40:21ZCognitive function and 10 year mortality in an 85 year-old community-dwelling population1178-1998https://doaj.org/article/f1b1527ae77e4784819fd836dbb60dd22014-10-01T00:00:00Zhttps://www.dovepress.com/cognitive-function-and-10-year-mortality-in-an-85-year-old-community-d-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Yutaka Takata,1 Toshihiro Ansai,2 Inho Soh,2 Shuji Awano,2 Ikuo Nakamichi,1 Sumio Akifusa,3 Kenichi Goto,1 Akihiro Yoshida,2 Hiroki Fujii,1 Ritsuko Fujisawa,1 Kazuo Sonoki31Division of General Internal Medicine, Kyushu Dental University, 2Division of Community Oral Health Development, Kyushu Dental University, 3Department of Oral Health and Environment, School of Oral Health Science, Kyushu Dental University, Kitakyushu, JapanAbstract: The relationship between mortality and impaired cognitive function has not been thoroughly investigated in a very elderly community-dwelling population, and little is known about the association of disease-specific mortality with Mini-Mental State Examination (MMSE) subscale scores. Here we evaluated these data in Japanese community-dwelling elderly. In 2003, 85 year-olds (n=207) were enrolled; 205 completed the MMSE for cognitive function and were followed-up for 10 years, during which time 120 participants died, 70 survived, and 17 were lost to follow-up. Thirty-eight deaths were due to cardiovascular disease, 22 to senility, 21 to respiratory disease, and 16 to cancer. All-cause mortality decreased by 4.3% with a 1-point increase in the global MMSE score without adjustment, and it decreased by 6.3% with adjustment for both sex and length of education. Cardiovascular mortality decreased by 7.6% and senility mortality decreased by 9.2% with a 1-point increase in the global MMSE score with adjustment for sex and education. No association was found between respiratory diseases or cancer mortality and global MMSE score. All-cause mortality also decreased with increases in MMSE subscale scores for time orientation, place orientation, delayed recall, naming objects, and listening and obeying. Cardiovascular mortality was also associated with the MMSE subscale of naming objects, and senility mortality was associated with the subscales of time orientation and place orientation. Thus, we found that impaired cognitive function determined by global MMSE score and some MMSE subscale scores were independent predictors of all-cause mortality or mortality due to cardiovascular disease or senility in 85 year-olds.Keywords: cognition, elderly, mortality, community-dwelling, MMSETakata YAnsai TSoh IAwano SNakamichi IAkifusa SGoto KYoshida AFujii HFujisawa RSonoki KDove Medical Pressarticlecognitionelderlymortalitycommunity-dwellingMMSEGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 1691-1699 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	cognition elderly mortality community-dwelling MMSE Geriatrics RC952-954.6
spellingShingle	cognition elderly mortality community-dwelling MMSE Geriatrics RC952-954.6 Takata Y Ansai T Soh I Awano S Nakamichi I Akifusa S Goto K Yoshida A Fujii H Fujisawa R Sonoki K Cognitive function and 10 year mortality in an 85 year-old community-dwelling population
description	Yutaka Takata,1 Toshihiro Ansai,2 Inho Soh,2 Shuji Awano,2 Ikuo Nakamichi,1 Sumio Akifusa,3 Kenichi Goto,1 Akihiro Yoshida,2 Hiroki Fujii,1 Ritsuko Fujisawa,1 Kazuo Sonoki31Division of General Internal Medicine, Kyushu Dental University, 2Division of Community Oral Health Development, Kyushu Dental University, 3Department of Oral Health and Environment, School of Oral Health Science, Kyushu Dental University, Kitakyushu, JapanAbstract: The relationship between mortality and impaired cognitive function has not been thoroughly investigated in a very elderly community-dwelling population, and little is known about the association of disease-specific mortality with Mini-Mental State Examination (MMSE) subscale scores. Here we evaluated these data in Japanese community-dwelling elderly. In 2003, 85 year-olds (n=207) were enrolled; 205 completed the MMSE for cognitive function and were followed-up for 10 years, during which time 120 participants died, 70 survived, and 17 were lost to follow-up. Thirty-eight deaths were due to cardiovascular disease, 22 to senility, 21 to respiratory disease, and 16 to cancer. All-cause mortality decreased by 4.3% with a 1-point increase in the global MMSE score without adjustment, and it decreased by 6.3% with adjustment for both sex and length of education. Cardiovascular mortality decreased by 7.6% and senility mortality decreased by 9.2% with a 1-point increase in the global MMSE score with adjustment for sex and education. No association was found between respiratory diseases or cancer mortality and global MMSE score. All-cause mortality also decreased with increases in MMSE subscale scores for time orientation, place orientation, delayed recall, naming objects, and listening and obeying. Cardiovascular mortality was also associated with the MMSE subscale of naming objects, and senility mortality was associated with the subscales of time orientation and place orientation. Thus, we found that impaired cognitive function determined by global MMSE score and some MMSE subscale scores were independent predictors of all-cause mortality or mortality due to cardiovascular disease or senility in 85 year-olds.Keywords: cognition, elderly, mortality, community-dwelling, MMSE
format	article
author	Takata Y Ansai T Soh I Awano S Nakamichi I Akifusa S Goto K Yoshida A Fujii H Fujisawa R Sonoki K
author_facet	Takata Y Ansai T Soh I Awano S Nakamichi I Akifusa S Goto K Yoshida A Fujii H Fujisawa R Sonoki K
author_sort	Takata Y
title	Cognitive function and 10 year mortality in an 85 year-old community-dwelling population
title_short	Cognitive function and 10 year mortality in an 85 year-old community-dwelling population
title_full	Cognitive function and 10 year mortality in an 85 year-old community-dwelling population
title_fullStr	Cognitive function and 10 year mortality in an 85 year-old community-dwelling population
title_full_unstemmed	Cognitive function and 10 year mortality in an 85 year-old community-dwelling population
title_sort	cognitive function and 10 year mortality in an 85 year-old community-dwelling population
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/f1b1527ae77e4784819fd836dbb60dd2
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Cognitive function and 10 year mortality in an 85 year-old community-dwelling population

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