Correlates of Uptake of Antiretroviral Therapy in HIV-Positive Orphans and Vulnerable Children Aged 0–14 Years in Tanzania
Amon Exavery,1 John Charles,1 Erica Kuhlik,2 Asheri Barankena,1 Amal Ally,1 Tumainiel Mbwambo,1 Christina Kyaruzi,1 Godfrey Martin Mubyazi,3 Levina Kikoyo,1 Elizabeth Jere1 1Pact, Dar es Salaam, Tanzania; 2Pact, Inc., Washington, DC, WA 20036, USA; 3National Institute for Medical Research (NIMR), Da...
Guardado en:
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2020
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/f1b9638292d744a38e6bed03006cfe43 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:f1b9638292d744a38e6bed03006cfe43 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:f1b9638292d744a38e6bed03006cfe432021-12-02T11:17:10ZCorrelates of Uptake of Antiretroviral Therapy in HIV-Positive Orphans and Vulnerable Children Aged 0–14 Years in Tanzania1179-1373https://doaj.org/article/f1b9638292d744a38e6bed03006cfe432020-07-01T00:00:00Zhttps://www.dovepress.com/correlates-of-uptake-of-antiretroviral-therapy-in-hiv-positive-orphans-peer-reviewed-article-HIVhttps://doaj.org/toc/1179-1373Amon Exavery,1 John Charles,1 Erica Kuhlik,2 Asheri Barankena,1 Amal Ally,1 Tumainiel Mbwambo,1 Christina Kyaruzi,1 Godfrey Martin Mubyazi,3 Levina Kikoyo,1 Elizabeth Jere1 1Pact, Dar es Salaam, Tanzania; 2Pact, Inc., Washington, DC, WA 20036, USA; 3National Institute for Medical Research (NIMR), Dar es Salaam, TanzaniaCorrespondence: Amon Exavery Email aexavery@pactworld.orgBackground: In 2018, only 65% of Tanzanian children aged 0– 14 years living with human immunodeficiency virus (HIV) were on treatment, suggesting that challenges exist. This study explores factors associated with uptake of antiretroviral therapy (ART) among HIV-positive orphans and vulnerable children (OVC).Methods: Data are from the USAID Kizazi Kipya project that aims to increase the uptake of HIV/AIDS and other health and social services by OVC and their caregivers. HIV-positive OVC aged 0– 14 years who were enrolled in the project from January 2017 to September 2018 were analyzed. ART status (off ART or on ART) was the outcome variable. Multivariate analysis was performed using multilevel logistic regression.Results: Of the 10,047 HIV-positive OVC aged 0– 14 years analyzed, 93.5% were currently on ART at enrollment. In the multivariate analysis, OVC with male caregivers were 4-times more likely than those with female caregivers to be on ART (OR=4.03, 95% CI=1.49– 10.90). OVC with HIV-positive caregivers were 12-times more likely than those with HIV-negative caregivers to be on ART (OR=12.0, 95% CI=3.81– 37.70). OVC with caregivers who did not disclose their HIV status were 74% less likely to be on ART than OVC of HIV-negative caregivers (OR=0.26, 95% CI=0.08– 0.90). OVC living in urban areas were more than 5-times as likely as their rural counterparts to be on ART (OR=5.55, 95% CI=2.21– 14.0).Conclusion: The majority of the OVCLHIV in the current study were currently on ART (93.5%) at enrollment. However, uptake of ART by the OVC was dependent on factors external to themselves. Advancing ART uptake may require targeting OVC of female caregivers, OVC of HIV-negative caregivers, as well as OVC of caregivers of undisclosed HIV statu, and rural areas.Keywords: antiretroviral therapy, uptake, 0– 14 years, orphans, vulnerable children, HIV, AIDS, TanzaniaExavery ACharles JKuhlik EBarankena AAlly AMbwambo TKyaruzi CMubyazi GMKikoyo LJere EDove Medical Pressarticleantiretroviral therapyuptake0-14 yearsorphansvulnerable childrenhivaidstanzaniaImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol Volume 12, Pp 233-241 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
antiretroviral therapy uptake 0-14 years orphans vulnerable children hiv aids tanzania Immunologic diseases. Allergy RC581-607 |
| spellingShingle |
antiretroviral therapy uptake 0-14 years orphans vulnerable children hiv aids tanzania Immunologic diseases. Allergy RC581-607 Exavery A Charles J Kuhlik E Barankena A Ally A Mbwambo T Kyaruzi C Mubyazi GM Kikoyo L Jere E Correlates of Uptake of Antiretroviral Therapy in HIV-Positive Orphans and Vulnerable Children Aged 0–14 Years in Tanzania |
| description |
Amon Exavery,1 John Charles,1 Erica Kuhlik,2 Asheri Barankena,1 Amal Ally,1 Tumainiel Mbwambo,1 Christina Kyaruzi,1 Godfrey Martin Mubyazi,3 Levina Kikoyo,1 Elizabeth Jere1 1Pact, Dar es Salaam, Tanzania; 2Pact, Inc., Washington, DC, WA 20036, USA; 3National Institute for Medical Research (NIMR), Dar es Salaam, TanzaniaCorrespondence: Amon Exavery Email aexavery@pactworld.orgBackground: In 2018, only 65% of Tanzanian children aged 0– 14 years living with human immunodeficiency virus (HIV) were on treatment, suggesting that challenges exist. This study explores factors associated with uptake of antiretroviral therapy (ART) among HIV-positive orphans and vulnerable children (OVC).Methods: Data are from the USAID Kizazi Kipya project that aims to increase the uptake of HIV/AIDS and other health and social services by OVC and their caregivers. HIV-positive OVC aged 0– 14 years who were enrolled in the project from January 2017 to September 2018 were analyzed. ART status (off ART or on ART) was the outcome variable. Multivariate analysis was performed using multilevel logistic regression.Results: Of the 10,047 HIV-positive OVC aged 0– 14 years analyzed, 93.5% were currently on ART at enrollment. In the multivariate analysis, OVC with male caregivers were 4-times more likely than those with female caregivers to be on ART (OR=4.03, 95% CI=1.49– 10.90). OVC with HIV-positive caregivers were 12-times more likely than those with HIV-negative caregivers to be on ART (OR=12.0, 95% CI=3.81– 37.70). OVC with caregivers who did not disclose their HIV status were 74% less likely to be on ART than OVC of HIV-negative caregivers (OR=0.26, 95% CI=0.08– 0.90). OVC living in urban areas were more than 5-times as likely as their rural counterparts to be on ART (OR=5.55, 95% CI=2.21– 14.0).Conclusion: The majority of the OVCLHIV in the current study were currently on ART (93.5%) at enrollment. However, uptake of ART by the OVC was dependent on factors external to themselves. Advancing ART uptake may require targeting OVC of female caregivers, OVC of HIV-negative caregivers, as well as OVC of caregivers of undisclosed HIV statu, and rural areas.Keywords: antiretroviral therapy, uptake, 0– 14 years, orphans, vulnerable children, HIV, AIDS, Tanzania |
| format |
article |
| author |
Exavery A Charles J Kuhlik E Barankena A Ally A Mbwambo T Kyaruzi C Mubyazi GM Kikoyo L Jere E |
| author_facet |
Exavery A Charles J Kuhlik E Barankena A Ally A Mbwambo T Kyaruzi C Mubyazi GM Kikoyo L Jere E |
| author_sort |
Exavery A |
| title |
Correlates of Uptake of Antiretroviral Therapy in HIV-Positive Orphans and Vulnerable Children Aged 0–14 Years in Tanzania |
| title_short |
Correlates of Uptake of Antiretroviral Therapy in HIV-Positive Orphans and Vulnerable Children Aged 0–14 Years in Tanzania |
| title_full |
Correlates of Uptake of Antiretroviral Therapy in HIV-Positive Orphans and Vulnerable Children Aged 0–14 Years in Tanzania |
| title_fullStr |
Correlates of Uptake of Antiretroviral Therapy in HIV-Positive Orphans and Vulnerable Children Aged 0–14 Years in Tanzania |
| title_full_unstemmed |
Correlates of Uptake of Antiretroviral Therapy in HIV-Positive Orphans and Vulnerable Children Aged 0–14 Years in Tanzania |
| title_sort |
correlates of uptake of antiretroviral therapy in hiv-positive orphans and vulnerable children aged 0–14 years in tanzania |
| publisher |
Dove Medical Press |
| publishDate |
2020 |
| url |
https://doaj.org/article/f1b9638292d744a38e6bed03006cfe43 |
| work_keys_str_mv |
AT exaverya correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania AT charlesj correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania AT kuhlike correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania AT barankenaa correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania AT allya correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania AT mbwambot correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania AT kyaruzic correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania AT mubyazigm correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania AT kikoyol correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania AT jeree correlatesofuptakeofantiretroviraltherapyinhivpositiveorphansandvulnerablechildrenaged0ndash14yearsintanzania |
| _version_ |
1718396090950090752 |