Alexander Disease

Main teaching point: The main differential diagnosis of leukodystrophy associated with macrocephaly consists of Alexander disease, Canavan disease, and megalencephalic leukodystrophy with subcortical cysts. Distinguishing imaging characteristics of Alexander disease are an apicoposterior gradient of...

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Détails bibliographiques
Auteurs principaux: Laura Hartog, Sven Dekeyzer, Stephanie Vanden Bossche
Format: article
Langue:EN
Publié: Ubiquity Press 2021
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Accès en ligne:https://doaj.org/article/f1c29a5c9ffa4f57947008adeaa3cf18
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Description
Résumé:Main teaching point: The main differential diagnosis of leukodystrophy associated with macrocephaly consists of Alexander disease, Canavan disease, and megalencephalic leukodystrophy with subcortical cysts. Distinguishing imaging characteristics of Alexander disease are an apicoposterior gradient of white matter involvement and a periventricular T2-hypointense rim.