Low-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation

Abstract This study develops an improved Feldkamp–Davis–Kress (FDK) reconstruction algorithm using non-local total variation (NLTV) denoising and a cubic B-spline interpolation-based backprojector to enhance the image quality of low-dose cone-beam computed tomography (CBCT). The NLTV objective funct...

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Autores principales:	Ho Lee, Jiyoung Park, Yeonho Choi, Kyung Ran Park, Byung Jun Min, Ik Jae Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f1cdc4c498234dda98ceaaf57d41d0eb
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spelling	oai:doaj.org-article:f1cdc4c498234dda98ceaaf57d41d0eb2021-12-02T14:11:31ZLow-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation10.1038/s41598-021-83266-12045-2322https://doaj.org/article/f1cdc4c498234dda98ceaaf57d41d0eb2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-83266-1https://doaj.org/toc/2045-2322Abstract This study develops an improved Feldkamp–Davis–Kress (FDK) reconstruction algorithm using non-local total variation (NLTV) denoising and a cubic B-spline interpolation-based backprojector to enhance the image quality of low-dose cone-beam computed tomography (CBCT). The NLTV objective function is minimized on all log-transformed projections using steepest gradient descent optimization with an adaptive control of the step size to augment the difference between a real structure and noise. The proposed algorithm was evaluated using a phantom data set acquired from a low-dose protocol with lower milliampere-seconds (mAs).The combination of NLTV minimization and cubic B-spline interpolation rendered the enhanced reconstruction images with significantly reduced noise compared to conventional FDK and local total variation with anisotropic penalty. The artifacts were remarkably suppressed in the reconstructed images. Quantitative analysis of reconstruction images using low-dose projections acquired from low mAs showed a contrast-to-noise ratio with spatial resolution comparable to images reconstructed using projections acquired from high mAs. The proposed approach produced the lowest RMSE and the highest correlation. These results indicate that the proposed algorithm enables application of the conventional FDK algorithm for low mAs image reconstruction in low-dose CBCT imaging, thereby eliminating the need for more computationally demanding algorithms. The substantial reductions in radiation exposure associated with the low mAs projection acquisition may facilitate wider practical applications of daily online CBCT imaging.Ho LeeJiyoung ParkYeonho ChoiKyung Ran ParkByung Jun MinIk Jae LeeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ho Lee Jiyoung Park Yeonho Choi Kyung Ran Park Byung Jun Min Ik Jae Lee Low-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation
description	Abstract This study develops an improved Feldkamp–Davis–Kress (FDK) reconstruction algorithm using non-local total variation (NLTV) denoising and a cubic B-spline interpolation-based backprojector to enhance the image quality of low-dose cone-beam computed tomography (CBCT). The NLTV objective function is minimized on all log-transformed projections using steepest gradient descent optimization with an adaptive control of the step size to augment the difference between a real structure and noise. The proposed algorithm was evaluated using a phantom data set acquired from a low-dose protocol with lower milliampere-seconds (mAs).The combination of NLTV minimization and cubic B-spline interpolation rendered the enhanced reconstruction images with significantly reduced noise compared to conventional FDK and local total variation with anisotropic penalty. The artifacts were remarkably suppressed in the reconstructed images. Quantitative analysis of reconstruction images using low-dose projections acquired from low mAs showed a contrast-to-noise ratio with spatial resolution comparable to images reconstructed using projections acquired from high mAs. The proposed approach produced the lowest RMSE and the highest correlation. These results indicate that the proposed algorithm enables application of the conventional FDK algorithm for low mAs image reconstruction in low-dose CBCT imaging, thereby eliminating the need for more computationally demanding algorithms. The substantial reductions in radiation exposure associated with the low mAs projection acquisition may facilitate wider practical applications of daily online CBCT imaging.
format	article
author	Ho Lee Jiyoung Park Yeonho Choi Kyung Ran Park Byung Jun Min Ik Jae Lee
author_facet	Ho Lee Jiyoung Park Yeonho Choi Kyung Ran Park Byung Jun Min Ik Jae Lee
author_sort	Ho Lee
title	Low-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation
title_short	Low-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation
title_full	Low-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation
title_fullStr	Low-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation
title_full_unstemmed	Low-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation
title_sort	low-dose cbct reconstruction via joint non-local total variation denoising and cubic b-spline interpolation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f1cdc4c498234dda98ceaaf57d41d0eb
work_keys_str_mv	AT holee lowdosecbctreconstructionviajointnonlocaltotalvariationdenoisingandcubicbsplineinterpolation AT jiyoungpark lowdosecbctreconstructionviajointnonlocaltotalvariationdenoisingandcubicbsplineinterpolation AT yeonhochoi lowdosecbctreconstructionviajointnonlocaltotalvariationdenoisingandcubicbsplineinterpolation AT kyungranpark lowdosecbctreconstructionviajointnonlocaltotalvariationdenoisingandcubicbsplineinterpolation AT byungjunmin lowdosecbctreconstructionviajointnonlocaltotalvariationdenoisingandcubicbsplineinterpolation AT ikjaelee lowdosecbctreconstructionviajointnonlocaltotalvariationdenoisingandcubicbsplineinterpolation
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Low-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation

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