A Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion

The 2013–2016 outbreak of Ebola virus disease in West Africa demonstrated the potential for previously localized outbreaks to turn into regional, or even global, health emergencies. With over 28,000 cases and 11,000 confirmed deaths, this outbreak was over 50 times as large as any previously record...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: J. Maximilian Fels, Robert H. Bortz, Tanwee Alkutkar, Eva Mittler, Rohit K. Jangra, Jennifer S. Spence, Kartik Chandran
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://doaj.org/article/f1d1e84b329f4c3899c090a268e3d590
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:f1d1e84b329f4c3899c090a268e3d590
record_format dspace
spelling oai:doaj.org-article:f1d1e84b329f4c3899c090a268e3d5902021-11-03T18:15:37ZA Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion2161-21292150-751110.1128/mBio.03616-20https://doaj.org/article/f1d1e84b329f4c3899c090a268e3d5902021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03616-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 The 2013–2016 outbreak of Ebola virus disease in West Africa demonstrated the potential for previously localized outbreaks to turn into regional, or even global, health emergencies. With over 28,000 cases and 11,000 confirmed deaths, this outbreak was over 50 times as large as any previously recorded.J. Maximilian FelsRobert H. BortzTanwee AlkutkarEva MittlerRohit K. JangraJennifer S. SpenceKartik ChandranAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
J. Maximilian Fels
Robert H. Bortz
Tanwee Alkutkar
Eva Mittler
Rohit K. Jangra
Jennifer S. Spence
Kartik Chandran
A Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion
description The 2013–2016 outbreak of Ebola virus disease in West Africa demonstrated the potential for previously localized outbreaks to turn into regional, or even global, health emergencies. With over 28,000 cases and 11,000 confirmed deaths, this outbreak was over 50 times as large as any previously recorded.
format article
author J. Maximilian Fels
Robert H. Bortz
Tanwee Alkutkar
Eva Mittler
Rohit K. Jangra
Jennifer S. Spence
Kartik Chandran
author_facet J. Maximilian Fels
Robert H. Bortz
Tanwee Alkutkar
Eva Mittler
Rohit K. Jangra
Jennifer S. Spence
Kartik Chandran
author_sort J. Maximilian Fels
title A Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion
title_short A Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion
title_full A Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion
title_fullStr A Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion
title_full_unstemmed A Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion
title_sort glycoprotein mutation that emerged during the 2013–2016 ebola virus epidemic alters proteolysis and accelerates membrane fusion
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/f1d1e84b329f4c3899c090a268e3d590
work_keys_str_mv AT jmaximilianfels aglycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT roberthbortz aglycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT tanweealkutkar aglycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT evamittler aglycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT rohitkjangra aglycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT jennifersspence aglycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT kartikchandran aglycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT jmaximilianfels glycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT roberthbortz glycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT tanweealkutkar glycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT evamittler glycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT rohitkjangra glycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT jennifersspence glycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
AT kartikchandran glycoproteinmutationthatemergedduringthe20132016ebolavirusepidemicaltersproteolysisandacceleratesmembranefusion
_version_ 1718445492535296000