Asymptomatic Carotid Disease and Cognitive Impairment: What Is the Evidence?

The development of cognitive dysfunction and dementia is a complex, multifactorial process. One of the contributors to various types of cognitive dysfunction is carotid atherosclerosis which can frequently be seen in asymptomatic individuals. There are a number of different manifestations of asympto...

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Autores principales:	Hediyeh Baradaran, Amir Hossein Sarrami, Ajay Gupta
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	carotid atherosclerosis cognitive impairment (CI) dementia carotid stenosis carotid plaque (CP) Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/f1d5eb10d94d4242a8a4c02b2d4677a9
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spelling	oai:doaj.org-article:f1d5eb10d94d4242a8a4c02b2d4677a92021-11-18T04:41:17ZAsymptomatic Carotid Disease and Cognitive Impairment: What Is the Evidence?1664-229510.3389/fneur.2021.741500https://doaj.org/article/f1d5eb10d94d4242a8a4c02b2d4677a92021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fneur.2021.741500/fullhttps://doaj.org/toc/1664-2295The development of cognitive dysfunction and dementia is a complex, multifactorial process. One of the contributors to various types of cognitive dysfunction is carotid atherosclerosis which can frequently be seen in asymptomatic individuals. There are a number of different manifestations of asymptomatic carotid atherosclerosis including arterial stiffness, carotid intima-media thickening, flow-limiting stenosis, and complex, atherosclerotic plaque. Each of these forms of atherosclerosis may contribute to cerebral parenchymal damage, contributing to cognitive dysfunction. In this review article, we will discuss each of these forms of carotid atherosclerosis, present the potential mechanistic underpinnings behind an association, and then review the scientific evidence supporting potential associations to cognitive dysfunction and dementia.Hediyeh BaradaranAmir Hossein SarramiAjay GuptaAjay GuptaFrontiers Media S.A.articlecarotid atherosclerosiscognitive impairment (CI)dementiacarotid stenosiscarotid plaque (CP)Neurology. Diseases of the nervous systemRC346-429ENFrontiers in Neurology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	carotid atherosclerosis cognitive impairment (CI) dementia carotid stenosis carotid plaque (CP) Neurology. Diseases of the nervous system RC346-429
spellingShingle	carotid atherosclerosis cognitive impairment (CI) dementia carotid stenosis carotid plaque (CP) Neurology. Diseases of the nervous system RC346-429 Hediyeh Baradaran Amir Hossein Sarrami Ajay Gupta Ajay Gupta Asymptomatic Carotid Disease and Cognitive Impairment: What Is the Evidence?
description	The development of cognitive dysfunction and dementia is a complex, multifactorial process. One of the contributors to various types of cognitive dysfunction is carotid atherosclerosis which can frequently be seen in asymptomatic individuals. There are a number of different manifestations of asymptomatic carotid atherosclerosis including arterial stiffness, carotid intima-media thickening, flow-limiting stenosis, and complex, atherosclerotic plaque. Each of these forms of atherosclerosis may contribute to cerebral parenchymal damage, contributing to cognitive dysfunction. In this review article, we will discuss each of these forms of carotid atherosclerosis, present the potential mechanistic underpinnings behind an association, and then review the scientific evidence supporting potential associations to cognitive dysfunction and dementia.
format	article
author	Hediyeh Baradaran Amir Hossein Sarrami Ajay Gupta Ajay Gupta
author_facet	Hediyeh Baradaran Amir Hossein Sarrami Ajay Gupta Ajay Gupta
author_sort	Hediyeh Baradaran
title	Asymptomatic Carotid Disease and Cognitive Impairment: What Is the Evidence?
title_short	Asymptomatic Carotid Disease and Cognitive Impairment: What Is the Evidence?
title_full	Asymptomatic Carotid Disease and Cognitive Impairment: What Is the Evidence?
title_fullStr	Asymptomatic Carotid Disease and Cognitive Impairment: What Is the Evidence?
title_full_unstemmed	Asymptomatic Carotid Disease and Cognitive Impairment: What Is the Evidence?
title_sort	asymptomatic carotid disease and cognitive impairment: what is the evidence?
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/f1d5eb10d94d4242a8a4c02b2d4677a9
work_keys_str_mv	AT hediyehbaradaran asymptomaticcarotiddiseaseandcognitiveimpairmentwhatistheevidence AT amirhosseinsarrami asymptomaticcarotiddiseaseandcognitiveimpairmentwhatistheevidence AT ajaygupta asymptomaticcarotiddiseaseandcognitiveimpairmentwhatistheevidence AT ajaygupta asymptomaticcarotiddiseaseandcognitiveimpairmentwhatistheevidence
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Asymptomatic Carotid Disease and Cognitive Impairment: What Is the Evidence?

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