Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesia.
<h4>Background</h4>In rodents, the development of dyskinesia produced by L-DOPA in the dopamine-depleted striatum occurs in response to increased dopamine D1 receptor-mediated activation of the cAMP - protein kinase A and of the Ras-extracellular signal-regulated kinase (ERK) signalling...
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Auteurs principaux: | Emanuela Santini, Veronique Sgambato-Faure, Qin Li, Marc Savasta, Sandra Dovero, Gilberto Fisone, Erwan Bezard |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2010
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Accès en ligne: | https://doaj.org/article/f1d6fedef81d4d898a7f2cf72f1af488 |
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