Plant DNA polymerases α and δ mediate replication of geminiviruses

Geminiviruses cause substantial damage to crops worldwide. Here Wu et al. show that geminivirus replication relies upon the host DNA polymerases α and δ, which produce double-stranded DNA intermediates and new copies of the viral genome, respectively, and is modulated by the viral C3 protein.

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Autores principales:	Mengshi Wu, Hua Wei, Huang Tan, Shaojun Pan, Qi Liu, Eduardo R. Bejarano, Rosa Lozano-Durán
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f1d9d94b57414e68b6a5f9176bb5daa8
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spelling	oai:doaj.org-article:f1d9d94b57414e68b6a5f9176bb5daa82021-12-02T15:54:54ZPlant DNA polymerases α and δ mediate replication of geminiviruses10.1038/s41467-021-23013-22041-1723https://doaj.org/article/f1d9d94b57414e68b6a5f9176bb5daa82021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23013-2https://doaj.org/toc/2041-1723Geminiviruses cause substantial damage to crops worldwide. Here Wu et al. show that geminivirus replication relies upon the host DNA polymerases α and δ, which produce double-stranded DNA intermediates and new copies of the viral genome, respectively, and is modulated by the viral C3 protein.Mengshi WuHua WeiHuang TanShaojun PanQi LiuEduardo R. BejaranoRosa Lozano-DuránNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mengshi Wu Hua Wei Huang Tan Shaojun Pan Qi Liu Eduardo R. Bejarano Rosa Lozano-Durán Plant DNA polymerases α and δ mediate replication of geminiviruses
description	Geminiviruses cause substantial damage to crops worldwide. Here Wu et al. show that geminivirus replication relies upon the host DNA polymerases α and δ, which produce double-stranded DNA intermediates and new copies of the viral genome, respectively, and is modulated by the viral C3 protein.
format	article
author	Mengshi Wu Hua Wei Huang Tan Shaojun Pan Qi Liu Eduardo R. Bejarano Rosa Lozano-Durán
author_facet	Mengshi Wu Hua Wei Huang Tan Shaojun Pan Qi Liu Eduardo R. Bejarano Rosa Lozano-Durán
author_sort	Mengshi Wu
title	Plant DNA polymerases α and δ mediate replication of geminiviruses
title_short	Plant DNA polymerases α and δ mediate replication of geminiviruses
title_full	Plant DNA polymerases α and δ mediate replication of geminiviruses
title_fullStr	Plant DNA polymerases α and δ mediate replication of geminiviruses
title_full_unstemmed	Plant DNA polymerases α and δ mediate replication of geminiviruses
title_sort	plant dna polymerases α and δ mediate replication of geminiviruses
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f1d9d94b57414e68b6a5f9176bb5daa8
work_keys_str_mv	AT mengshiwu plantdnapolymerasesaanddmediatereplicationofgeminiviruses AT huawei plantdnapolymerasesaanddmediatereplicationofgeminiviruses AT huangtan plantdnapolymerasesaanddmediatereplicationofgeminiviruses AT shaojunpan plantdnapolymerasesaanddmediatereplicationofgeminiviruses AT qiliu plantdnapolymerasesaanddmediatereplicationofgeminiviruses AT eduardorbejarano plantdnapolymerasesaanddmediatereplicationofgeminiviruses AT rosalozanoduran plantdnapolymerasesaanddmediatereplicationofgeminiviruses
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Plant DNA polymerases α and δ mediate replication of geminiviruses

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