Plant DNA polymerases α and δ mediate replication of geminiviruses
Geminiviruses cause substantial damage to crops worldwide. Here Wu et al. show that geminivirus replication relies upon the host DNA polymerases α and δ, which produce double-stranded DNA intermediates and new copies of the viral genome, respectively, and is modulated by the viral C3 protein.
Enregistré dans:
Auteurs principaux: | Mengshi Wu, Hua Wei, Huang Tan, Shaojun Pan, Qi Liu, Eduardo R. Bejarano, Rosa Lozano-Durán |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f1d9d94b57414e68b6a5f9176bb5daa8 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
par: Zhi-Xiong Zhou, et autres
Publié: (2019) -
Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
par: Marta A. Garbacz, et autres
Publié: (2018) -
Geminiviruses encode additional small proteins with specific subcellular localizations and virulence function
par: Pan Gong, et autres
Publié: (2021) -
Small but mighty: Functional landscape of the versatile geminivirus-encoded C4 protein.
par: Laura Medina-Puche, et autres
Publié: (2021) -
The 3.3 Å structure of a plant geminivirus using cryo-EM
par: Emma L. Hesketh, et autres
Publié: (2018)