Plant DNA polymerases α and δ mediate replication of geminiviruses
Geminiviruses cause substantial damage to crops worldwide. Here Wu et al. show that geminivirus replication relies upon the host DNA polymerases α and δ, which produce double-stranded DNA intermediates and new copies of the viral genome, respectively, and is modulated by the viral C3 protein.
Saved in:
Main Authors: | Mengshi Wu, Hua Wei, Huang Tan, Shaojun Pan, Qi Liu, Eduardo R. Bejarano, Rosa Lozano-Durán |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/f1d9d94b57414e68b6a5f9176bb5daa8 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
by: Zhi-Xiong Zhou, et al.
Published: (2019) -
Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
by: Marta A. Garbacz, et al.
Published: (2018) -
Geminiviruses encode additional small proteins with specific subcellular localizations and virulence function
by: Pan Gong, et al.
Published: (2021) -
Small but mighty: Functional landscape of the versatile geminivirus-encoded C4 protein.
by: Laura Medina-Puche, et al.
Published: (2021) -
The 3.3 Å structure of a plant geminivirus using cryo-EM
by: Emma L. Hesketh, et al.
Published: (2018)