Endothelial-specific depletion of TGF-β signaling affects lymphatic function

Endothelial-specific depletion of TGF-β signaling affects lymphatic function

Abstract Background Transforming growth factor (TGF)-β is a multifunctional cytokine involved in cell differentiation, cell proliferation, and tissue homeostasis. Although TGF-β signaling is essential for maintaining blood vessel functions, little is known about the role of TGF-β in lymphatic homeos...

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Autores principales: Kunpei Fukasawa, Kako Hanada, Kei Ichikawa, Masanori Hirashima, Takahiro Takagi, Susumu Itoh, Testuro Watabe, Fumiko Itoh
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
TGF-β
Lymphatic vessel
Endothelial cell
Prox1
Tumor metastasis
Pathology
RB1-214
Acceso en línea:https://doaj.org/article/f1dce799d34944ca932abddf07f07cd3
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https://doaj.org/article/f1dce799d34944ca932abddf07f07cd3

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