Liver cirrosis and complication risk management

Liver cirrhosis (LC) takes the main place in the structure of the pathology of the digestive system in terms of the frequency of mortality, as well as in the development of fatal and poorly controlled complications, which requires the search for effective methods for preventing the progression of th...

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Autores principales:	Igor G. Bakulin, Inna A. Oganezova, Maria I. Skalinskaya, Ekaterina V. Skazyvaeva
Formato:	article
Lenguaje:	RU
Publicado:	"Consilium Medicum" Publishing house 2021
Materias:	liver cirrhosis complications of liver cirrhosis intestinal microbiota increased intestinal permeability Medicine R
Acceso en línea:	https://doaj.org/article/f1e3a9ad7e9f488eb530620e573a618a
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spelling	oai:doaj.org-article:f1e3a9ad7e9f488eb530620e573a618a2021-12-01T12:22:36ZLiver cirrosis and complication risk management0040-36602309-534210.26442/00403660.2021.08.200917https://doaj.org/article/f1e3a9ad7e9f488eb530620e573a618a2021-08-01T00:00:00Zhttps://ter-arkhiv.ru/0040-3660/article/viewFile/79591/60207https://doaj.org/toc/0040-3660https://doaj.org/toc/2309-5342Liver cirrhosis (LC) takes the main place in the structure of the pathology of the digestive system in terms of the frequency of mortality, as well as in the development of fatal and poorly controlled complications, which requires the search for effective methods for preventing the progression of the disease and the development of complications. The article provides updated information on the role of the intestinal microbiota, as well as endotoxemia and increased intestinal permeability syndromes in the pathophysiology of LC and its complications. The results of recent meta-analyses of the impact of dysbiotic disorders on the prognosis of the LC and the options for their correction are presented. Understanding of the significance of involvement of gut microbiota in the pathogenesis of LC has become one of the levers of management of the risks of complications of LC. In this case, the livergut axis can be considered to be the leading link to the formation of most of the main complications of LC.Igor G. BakulinInna A. OganezovaMaria I. SkalinskayaEkaterina V. Skazyvaeva"Consilium Medicum" Publishing housearticleliver cirrhosiscomplications of liver cirrhosisintestinal microbiotaincreased intestinal permeabilityMedicineRRUТерапевтический архив, Vol 93, Iss 8, Pp 963-968 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	liver cirrhosis complications of liver cirrhosis intestinal microbiota increased intestinal permeability Medicine R
spellingShingle	liver cirrhosis complications of liver cirrhosis intestinal microbiota increased intestinal permeability Medicine R Igor G. Bakulin Inna A. Oganezova Maria I. Skalinskaya Ekaterina V. Skazyvaeva Liver cirrosis and complication risk management
description	Liver cirrhosis (LC) takes the main place in the structure of the pathology of the digestive system in terms of the frequency of mortality, as well as in the development of fatal and poorly controlled complications, which requires the search for effective methods for preventing the progression of the disease and the development of complications. The article provides updated information on the role of the intestinal microbiota, as well as endotoxemia and increased intestinal permeability syndromes in the pathophysiology of LC and its complications. The results of recent meta-analyses of the impact of dysbiotic disorders on the prognosis of the LC and the options for their correction are presented. Understanding of the significance of involvement of gut microbiota in the pathogenesis of LC has become one of the levers of management of the risks of complications of LC. In this case, the livergut axis can be considered to be the leading link to the formation of most of the main complications of LC.
format	article
author	Igor G. Bakulin Inna A. Oganezova Maria I. Skalinskaya Ekaterina V. Skazyvaeva
author_facet	Igor G. Bakulin Inna A. Oganezova Maria I. Skalinskaya Ekaterina V. Skazyvaeva
author_sort	Igor G. Bakulin
title	Liver cirrosis and complication risk management
title_short	Liver cirrosis and complication risk management
title_full	Liver cirrosis and complication risk management
title_fullStr	Liver cirrosis and complication risk management
title_full_unstemmed	Liver cirrosis and complication risk management
title_sort	liver cirrosis and complication risk management
publisher	"Consilium Medicum" Publishing house
publishDate	2021
url	https://doaj.org/article/f1e3a9ad7e9f488eb530620e573a618a
work_keys_str_mv	AT igorgbakulin livercirrosisandcomplicationriskmanagement AT innaaoganezova livercirrosisandcomplicationriskmanagement AT mariaiskalinskaya livercirrosisandcomplicationriskmanagement AT ekaterinavskazyvaeva livercirrosisandcomplicationriskmanagement
_version_	1718405210003472384

Liver cirrosis and complication risk management

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