Lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin

Michael McClintock,1 Mathew W MacCumber1,2 1Department of Ophthalmology, Rush University Medical Center, 2Illinois Retina Associates, S.C., Chicago, IL, USA Abstract: We report the case of a glaucoma patient who received a single intravitreal injection of 125 µg ocriplasmin for...

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Autores principales:	McClintock M, MacCumber MW
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f1eb3d29fc9e47cbb3d87967e8d6b1d8
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spelling	oai:doaj.org-article:f1eb3d29fc9e47cbb3d87967e8d6b1d82021-12-02T06:01:17ZLowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin1177-5483https://doaj.org/article/f1eb3d29fc9e47cbb3d87967e8d6b1d82015-10-01T00:00:00Zhttps://www.dovepress.com/lowered-intraocular-pressure-in-a-glaucoma-patient-after-intravitreal--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Michael McClintock,1 Mathew W MacCumber1,2 1Department of Ophthalmology, Rush University Medical Center, 2Illinois Retina Associates, S.C., Chicago, IL, USA Abstract: We report the case of a glaucoma patient who received a single intravitreal injection of 125 µg ocriplasmin for vitreomacular traction in the right eye. The patient had bilateral advanced glaucoma and had previously undergone an implantation of an Ahmed glaucoma valve in the right eye and trabeculectomy in both eyes. The patient was using three topical ophthalmic intraocular pressure (IOP)-lowering medications on the day of injection. Baseline uncorrected Snellen visual acuity was 20/80-1 and IOP was 19 mmHg. Resolution of vitreomacular traction was achieved 1 week after injection. IOP was transiently decreased, reaching a maximum reduction of 12 mmHg below baseline at 1 month after injection, when serous choroidal effusion was also present. IOP returned to baseline levels and choroidal effusion resolved at 2 months after injection of IOP-lowering medication. Vitrectomy with epiretinal membrane and internal limiting membrane peeling, endolaser photocoagulation, and fluid–gas exchange were performed in the right eye ~3.5 months after injection to treat persistent epiretinal membrane, and presumed tractional retinal detachment. Final visual acuity was 20/50+ and IOP was 18 mmHg at 16 weeks after surgery. To our knowledge, this is the first report of IOP reduction and serous choroidal effusion after ocriplasmin injection. Keywords: ocriplasmin, intraocular pressure, vitrectomy, choroidal effusionMcClintock MMacCumber MWDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 1995-1998 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 McClintock M MacCumber MW Lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin
description	Michael McClintock,1 Mathew W MacCumber1,2 1Department of Ophthalmology, Rush University Medical Center, 2Illinois Retina Associates, S.C., Chicago, IL, USA Abstract: We report the case of a glaucoma patient who received a single intravitreal injection of 125 µg ocriplasmin for vitreomacular traction in the right eye. The patient had bilateral advanced glaucoma and had previously undergone an implantation of an Ahmed glaucoma valve in the right eye and trabeculectomy in both eyes. The patient was using three topical ophthalmic intraocular pressure (IOP)-lowering medications on the day of injection. Baseline uncorrected Snellen visual acuity was 20/80-1 and IOP was 19 mmHg. Resolution of vitreomacular traction was achieved 1 week after injection. IOP was transiently decreased, reaching a maximum reduction of 12 mmHg below baseline at 1 month after injection, when serous choroidal effusion was also present. IOP returned to baseline levels and choroidal effusion resolved at 2 months after injection of IOP-lowering medication. Vitrectomy with epiretinal membrane and internal limiting membrane peeling, endolaser photocoagulation, and fluid–gas exchange were performed in the right eye ~3.5 months after injection to treat persistent epiretinal membrane, and presumed tractional retinal detachment. Final visual acuity was 20/50+ and IOP was 18 mmHg at 16 weeks after surgery. To our knowledge, this is the first report of IOP reduction and serous choroidal effusion after ocriplasmin injection. Keywords: ocriplasmin, intraocular pressure, vitrectomy, choroidal effusion
format	article
author	McClintock M MacCumber MW
author_facet	McClintock M MacCumber MW
author_sort	McClintock M
title	Lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin
title_short	Lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin
title_full	Lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin
title_fullStr	Lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin
title_full_unstemmed	Lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin
title_sort	lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/f1eb3d29fc9e47cbb3d87967e8d6b1d8
work_keys_str_mv	AT mcclintockm loweredintraocularpressureinaglaucomapatientafterintravitrealinjectionofocriplasmin AT maccumbermw loweredintraocularpressureinaglaucomapatientafterintravitrealinjectionofocriplasmin
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Lowered intraocular pressure in a glaucoma patient after intravitreal injection of ocriplasmin

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