An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling

The cystic cavity that develops following injuries to brain or spinal cord is a major obstacle. Here the authors show an injection of imidazole poly(organophosphazenes), a hydrogel with thermosensitive sol–gel transition behavior, almost completely eliminates cystic cavities in a clinically relevant...

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Autores principales:	Le Thi Anh Hong, Young-Min Kim, Hee Hwan Park, Dong Hoon Hwang, Yuexian Cui, Eun Mi Lee, Stephanie Yahn, Jae K. Lee, Soo-Chang Song, Byung Gon Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f1ef677ce24a49e5b92880944ff2a393
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:f1ef677ce24a49e5b92880944ff2a3932021-12-02T17:01:23ZAn injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling10.1038/s41467-017-00583-82041-1723https://doaj.org/article/f1ef677ce24a49e5b92880944ff2a3932017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00583-8https://doaj.org/toc/2041-1723The cystic cavity that develops following injuries to brain or spinal cord is a major obstacle. Here the authors show an injection of imidazole poly(organophosphazenes), a hydrogel with thermosensitive sol–gel transition behavior, almost completely eliminates cystic cavities in a clinically relevant rat spinal cord injury model.Le Thi Anh HongYoung-Min KimHee Hwan ParkDong Hoon HwangYuexian CuiEun Mi LeeStephanie YahnJae K. LeeSoo-Chang SongByung Gon KimNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Le Thi Anh Hong Young-Min Kim Hee Hwan Park Dong Hoon Hwang Yuexian Cui Eun Mi Lee Stephanie Yahn Jae K. Lee Soo-Chang Song Byung Gon Kim An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling
description	The cystic cavity that develops following injuries to brain or spinal cord is a major obstacle. Here the authors show an injection of imidazole poly(organophosphazenes), a hydrogel with thermosensitive sol–gel transition behavior, almost completely eliminates cystic cavities in a clinically relevant rat spinal cord injury model.
format	article
author	Le Thi Anh Hong Young-Min Kim Hee Hwan Park Dong Hoon Hwang Yuexian Cui Eun Mi Lee Stephanie Yahn Jae K. Lee Soo-Chang Song Byung Gon Kim
author_facet	Le Thi Anh Hong Young-Min Kim Hee Hwan Park Dong Hoon Hwang Yuexian Cui Eun Mi Lee Stephanie Yahn Jae K. Lee Soo-Chang Song Byung Gon Kim
author_sort	Le Thi Anh Hong
title	An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling
title_short	An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling
title_full	An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling
title_fullStr	An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling
title_full_unstemmed	An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling
title_sort	injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f1ef677ce24a49e5b92880944ff2a393
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An injectable hydrogel enhances tissue repair after spinal cord injury by promoting extracellular matrix remodeling

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