Determining Appropriate Screening Tools and Cutoffs for Cognitive Impairment in the Chinese Elderly

Background: The Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) are the most commonly used tools for cognitive impairment screening. The present study aimed to investigate the ability of the MOCA and MMSE to differentiate between cognitively normal elderly individuals,...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Shaowei Zhang, Qi Qiu, Shixing Qian, Xiang Lin, Feng Yan, Lin Sun, Shifu Xiao, Jinghua Wang, Yuan Fang, Xia Li
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	Mini-Mental State Exam (MMSE) Montreal Cognitive Assessment (MoCA) mild cognitive impairment (MCI) dementia China Psychiatry RC435-571
Acceso en línea:	https://doaj.org/article/f1fa58485bf8453e97533ebe590bfa9a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f1fa58485bf8453e97533ebe590bfa9a
record_format	dspace
spelling	oai:doaj.org-article:f1fa58485bf8453e97533ebe590bfa9a2021-12-02T10:32:12ZDetermining Appropriate Screening Tools and Cutoffs for Cognitive Impairment in the Chinese Elderly1664-064010.3389/fpsyt.2021.773281https://doaj.org/article/f1fa58485bf8453e97533ebe590bfa9a2021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fpsyt.2021.773281/fullhttps://doaj.org/toc/1664-0640Background: The Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) are the most commonly used tools for cognitive impairment screening. The present study aimed to investigate the ability of the MOCA and MMSE to differentiate between cognitively normal elderly individuals, MCI patients and dementia patients at different ages and education levels and to establish the optimal cutoff scores of the MoCA and MMSE for MCI and dementia in the Chinese elderly.Methods: A total of 2,954 Chinese elderly individuals, including 1,746 normal controls, 599 MCI patients and 249 dementia patients, were consecutively recruited in the study. The optimal cutoffs for MoCA and MMSE were determined using receiver operating characteristic (ROC) analysis among the different age and education levels in the three groups. Furthermore, comparison of ROC curves were made to evaluate the performances of the two tests.Results: The area under the curve(AUC) of the MoCA (0.82) for detecting MCI was significantly higher than that of the MMSE (0.75) (P < 0.001). When the sample was divided according to age and education level, the AUC of the MoCA (0.84) was higher than those of the MMSE (0.71) for MCI (P < 0.001) in the younger and more highly-educated groups. The optimal cutoff scores of the MoCA for the groups aged ≤ 75 years old and education ≤ 6 years, aged > 75 years old and education ≤ 6 years, aged ≤ 75 years old and education > 6 years, aged > 75 years old and education > 6 years in screening for MCI were identified as 19.5, 15.5, 24.5 and 24.5, respectively, and the optimal cutoff scores for dementia were 18.5, 10.5, 18.5 and 20.5, respectively. For MMSE in the above four groups, the cutoff scores to detect MCI were 26.5, 22.5, 28.5 and 26.5, respectively, and the optimal cutoff scores for dementia were 23.5, 19.5, 23.5 and 23.5, respectively.Conclusion: Compared to MMSE, the MoCA is more suitable for discriminating MCI in younger and more highly educated elderly Chinese individuals. However, the MMSE has advantage over MoCA in screening MCI in individuals with lower education levels and the older groups of Chinese elderly.Shaowei ZhangQi QiuShixing QianXiang LinFeng YanLin SunShifu XiaoJinghua WangYuan FangXia LiFrontiers Media S.A.articleMini-Mental State Exam (MMSE)Montreal Cognitive Assessment (MoCA)mild cognitive impairment (MCI)dementiaChinaPsychiatryRC435-571ENFrontiers in Psychiatry, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Mini-Mental State Exam (MMSE) Montreal Cognitive Assessment (MoCA) mild cognitive impairment (MCI) dementia China Psychiatry RC435-571
spellingShingle	Mini-Mental State Exam (MMSE) Montreal Cognitive Assessment (MoCA) mild cognitive impairment (MCI) dementia China Psychiatry RC435-571 Shaowei Zhang Qi Qiu Shixing Qian Xiang Lin Feng Yan Lin Sun Shifu Xiao Jinghua Wang Yuan Fang Xia Li Determining Appropriate Screening Tools and Cutoffs for Cognitive Impairment in the Chinese Elderly
description	Background: The Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) are the most commonly used tools for cognitive impairment screening. The present study aimed to investigate the ability of the MOCA and MMSE to differentiate between cognitively normal elderly individuals, MCI patients and dementia patients at different ages and education levels and to establish the optimal cutoff scores of the MoCA and MMSE for MCI and dementia in the Chinese elderly.Methods: A total of 2,954 Chinese elderly individuals, including 1,746 normal controls, 599 MCI patients and 249 dementia patients, were consecutively recruited in the study. The optimal cutoffs for MoCA and MMSE were determined using receiver operating characteristic (ROC) analysis among the different age and education levels in the three groups. Furthermore, comparison of ROC curves were made to evaluate the performances of the two tests.Results: The area under the curve(AUC) of the MoCA (0.82) for detecting MCI was significantly higher than that of the MMSE (0.75) (P < 0.001). When the sample was divided according to age and education level, the AUC of the MoCA (0.84) was higher than those of the MMSE (0.71) for MCI (P < 0.001) in the younger and more highly-educated groups. The optimal cutoff scores of the MoCA for the groups aged ≤ 75 years old and education ≤ 6 years, aged > 75 years old and education ≤ 6 years, aged ≤ 75 years old and education > 6 years, aged > 75 years old and education > 6 years in screening for MCI were identified as 19.5, 15.5, 24.5 and 24.5, respectively, and the optimal cutoff scores for dementia were 18.5, 10.5, 18.5 and 20.5, respectively. For MMSE in the above four groups, the cutoff scores to detect MCI were 26.5, 22.5, 28.5 and 26.5, respectively, and the optimal cutoff scores for dementia were 23.5, 19.5, 23.5 and 23.5, respectively.Conclusion: Compared to MMSE, the MoCA is more suitable for discriminating MCI in younger and more highly educated elderly Chinese individuals. However, the MMSE has advantage over MoCA in screening MCI in individuals with lower education levels and the older groups of Chinese elderly.
format	article
author	Shaowei Zhang Qi Qiu Shixing Qian Xiang Lin Feng Yan Lin Sun Shifu Xiao Jinghua Wang Yuan Fang Xia Li
author_facet	Shaowei Zhang Qi Qiu Shixing Qian Xiang Lin Feng Yan Lin Sun Shifu Xiao Jinghua Wang Yuan Fang Xia Li
author_sort	Shaowei Zhang
title	Determining Appropriate Screening Tools and Cutoffs for Cognitive Impairment in the Chinese Elderly
title_short	Determining Appropriate Screening Tools and Cutoffs for Cognitive Impairment in the Chinese Elderly
title_full	Determining Appropriate Screening Tools and Cutoffs for Cognitive Impairment in the Chinese Elderly
title_fullStr	Determining Appropriate Screening Tools and Cutoffs for Cognitive Impairment in the Chinese Elderly
title_full_unstemmed	Determining Appropriate Screening Tools and Cutoffs for Cognitive Impairment in the Chinese Elderly
title_sort	determining appropriate screening tools and cutoffs for cognitive impairment in the chinese elderly
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/f1fa58485bf8453e97533ebe590bfa9a
work_keys_str_mv	AT shaoweizhang determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly AT qiqiu determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly AT shixingqian determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly AT xianglin determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly AT fengyan determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly AT linsun determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly AT shifuxiao determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly AT jinghuawang determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly AT yuanfang determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly AT xiali determiningappropriatescreeningtoolsandcutoffsforcognitiveimpairmentinthechineseelderly
_version_	1718397096088829952

Determining Appropriate Screening Tools and Cutoffs for Cognitive Impairment in the Chinese Elderly

Ejemplares similares