TBCD links centriologenesis, spindle microtubule dynamics, and midbody abscission in human cells.

Microtubule-organizing centers recruit alpha- and beta-tubulin polypeptides for microtubule nucleation. Tubulin synthesis is complex, requiring five specific cofactors, designated tubulin cofactors (TBCs) A-E, which contribute to various aspects of microtubule dynamics in vivo. Here, we show that tu...

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Autores principales: Mónica López Fanarraga, Javier Bellido, Cristina Jaén, Juan Carlos Villegas, Juan Carlos Zabala
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/f1fe0b63fff84631a5a5d7f6373dbfd0
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