Structural basis for the target specificity of actin histidine methyltransferase SETD3

SETD3 is the first known metazoan protein histidine methyltransferase but the molecular basis for its target specificity is unclear. Here, the authors elucidate the structural and molecular determinants for the histidine specificity of SETD3.

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Autores principales: Shaobo Dai, John R. Horton, Clayton B. Woodcock, Alex W. Wilkinson, Xing Zhang, Or Gozani, Xiaodong Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f2129526184a4597af28ea92c757a4b4
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