Illuminating the off-pathway nature of the molten globule folding intermediate of an α-β parallel protein.
Partially folded protein species transiently form during folding of most proteins. Often, these species are molten globules, which may be on- or off-pathway to the native state. Molten globules are ensembles of interconverting protein conformers that have a substantial amount of secondary structure,...
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Autores principales: | Simon Lindhoud, Adrie H Westphal, Jan Willem Borst, Carlo P M van Mierlo |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/f23206c8ed51454bb2f166448be6d726 |
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