A comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group

Background: caudal anaesthesia has shortterm effect. Alpha2 adenoreceptors when used as adjuvant to local anaesthetic in children prolongs analgesic duration. The study is aimed to assess the efficacy of addition of dexmedetomidine with Bupivacaine in caudal block for extending postoperative ana...

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Autores principales:	Kishore Kumar N., Sandeep Kadam
Formato:	article
Lenguaje:	EN RU UK
Publicado:	Interdisciplinary Academy of Pain Medicine 2021
Materias:	bupivacaine dexmedetomidine hemodynamics postoperative pain Anesthesiology RD78.3-87.3
Acceso en línea:	https://doaj.org/article/f236cfaf00ab468397c8416a248e4365
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spelling	oai:doaj.org-article:f236cfaf00ab468397c8416a248e43652021-11-15T14:30:59ZA comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group10.31636/pmjua.v6i3.32414-38122519-2752https://doaj.org/article/f236cfaf00ab468397c8416a248e43652021-11-01T00:00:00Zhttps://painmedicine.org.ua/index.php/pnmdcn/article/view/268https://doaj.org/toc/2414-3812https://doaj.org/toc/2519-2752 Background: caudal anaesthesia has shortterm effect. Alpha2 adenoreceptors when used as adjuvant to local anaesthetic in children prolongs analgesic duration. The study is aimed to assess the efficacy of addition of dexmedetomidine with Bupivacaine in caudal block for extending postoperative analgesia and its safety profile in pediatric infraumbilical surgeries. Method: the prospective interventional longitudinal double blinded study was conducted on 60 patients randomly divided into two groups by simple lottery method: group B who received (0.25 %) bupivacaine 1 ml/kg plus 1 ml normal saline (NS), and those in group BD who received (0.25 %) bupivacaine 1 ml/kg plus 0.5 μg/kg dexmedetomidine in 1 ml NS. Postsurgery, both groups were compared in R studio v1.2.5001. Association between the adverse effect and other variables (age, gender, type of surgery, groups) were assessed by Multiple linear regression. Results: in group BD, duration of analgesia prolonged significantly (P < 0.05). In group BD, FLACC score at initial four hours and at 12th hour was significantly less (P < 0.05). Group B was more likely to receive high number of rescue analgesia (P = 0.0005; OR = 11.769). No significant difference was observed concerning hemodynamics, respiratory parameters and adverse effect between both groups (P > 0.05). Conclusion: in children, dexmedetomidine when used along with bupivacaine prolongs postoperative analgesia duration, without any significant side effects. Kishore Kumar N.Sandeep KadamInterdisciplinary Academy of Pain Medicinearticlebupivacainedexmedetomidinehemodynamicspostoperative painAnesthesiologyRD78.3-87.3ENRUUKМедицина болю, Vol 6, Iss 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN RU UK
topic	bupivacaine dexmedetomidine hemodynamics postoperative pain Anesthesiology RD78.3-87.3
spellingShingle	bupivacaine dexmedetomidine hemodynamics postoperative pain Anesthesiology RD78.3-87.3 Kishore Kumar N. Sandeep Kadam A comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group
description	Background: caudal anaesthesia has shortterm effect. Alpha2 adenoreceptors when used as adjuvant to local anaesthetic in children prolongs analgesic duration. The study is aimed to assess the efficacy of addition of dexmedetomidine with Bupivacaine in caudal block for extending postoperative analgesia and its safety profile in pediatric infraumbilical surgeries. Method: the prospective interventional longitudinal double blinded study was conducted on 60 patients randomly divided into two groups by simple lottery method: group B who received (0.25 %) bupivacaine 1 ml/kg plus 1 ml normal saline (NS), and those in group BD who received (0.25 %) bupivacaine 1 ml/kg plus 0.5 μg/kg dexmedetomidine in 1 ml NS. Postsurgery, both groups were compared in R studio v1.2.5001. Association between the adverse effect and other variables (age, gender, type of surgery, groups) were assessed by Multiple linear regression. Results: in group BD, duration of analgesia prolonged significantly (P < 0.05). In group BD, FLACC score at initial four hours and at 12th hour was significantly less (P < 0.05). Group B was more likely to receive high number of rescue analgesia (P = 0.0005; OR = 11.769). No significant difference was observed concerning hemodynamics, respiratory parameters and adverse effect between both groups (P > 0.05). Conclusion: in children, dexmedetomidine when used along with bupivacaine prolongs postoperative analgesia duration, without any significant side effects.
format	article
author	Kishore Kumar N. Sandeep Kadam
author_facet	Kishore Kumar N. Sandeep Kadam
author_sort	Kishore Kumar N.
title	A comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group
title_short	A comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group
title_full	A comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group
title_fullStr	A comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group
title_full_unstemmed	A comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group
title_sort	comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group
publisher	Interdisciplinary Academy of Pain Medicine
publishDate	2021
url	https://doaj.org/article/f236cfaf00ab468397c8416a248e4365
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A comparative study of caudal anesthesia with bupivacaine v/s bupivacaine with dexmedetomidine in lower abdominal surgeries in pediatric age group

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