An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos

An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos

Early human embryonic development involves extensive changes in chromatin structure and transcriptional activity. Here the authors present LiCAT-seq, a method enabling simultaneous profiling of chromatin accessibility and gene expression with ultra-low input of cells and map chromatin accessibility...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Longqi Liu, Lizhi Leng, Chuanyu Liu, Changfu Lu, Yue Yuan, Liang Wu, Fei Gong, Shuoping Zhang, Xiaoyu Wei, Mingyue Wang, Lei Zhao, Liang Hu, Jian Wang, Huanming Yang, Shida Zhu, Fang Chen, Guangxiu Lu, Zhouchun Shang, Ge Lin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/f2377bee5d8a4fa08fc7cda946aac81e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:f2377bee5d8a4fa08fc7cda946aac81e
record_format dspace
spelling oai:doaj.org-article:f2377bee5d8a4fa08fc7cda946aac81e2021-12-02T17:01:33ZAn integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos10.1038/s41467-018-08244-02041-1723https://doaj.org/article/f2377bee5d8a4fa08fc7cda946aac81e2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08244-0https://doaj.org/toc/2041-1723Early human embryonic development involves extensive changes in chromatin structure and transcriptional activity. Here the authors present LiCAT-seq, a method enabling simultaneous profiling of chromatin accessibility and gene expression with ultra-low input of cells and map chromatin accessibility and transcriptome landscapes for human pre-implantation embryos.Longqi LiuLizhi LengChuanyu LiuChangfu LuYue YuanLiang WuFei GongShuoping ZhangXiaoyu WeiMingyue WangLei ZhaoLiang HuJian WangHuanming YangShida ZhuFang ChenGuangxiu LuZhouchun ShangGe LinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Longqi Liu
Lizhi Leng
Chuanyu Liu
Changfu Lu
Yue Yuan
Liang Wu
Fei Gong
Shuoping Zhang
Xiaoyu Wei
Mingyue Wang
Lei Zhao
Liang Hu
Jian Wang
Huanming Yang
Shida Zhu
Fang Chen
Guangxiu Lu
Zhouchun Shang
Ge Lin
An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
description Early human embryonic development involves extensive changes in chromatin structure and transcriptional activity. Here the authors present LiCAT-seq, a method enabling simultaneous profiling of chromatin accessibility and gene expression with ultra-low input of cells and map chromatin accessibility and transcriptome landscapes for human pre-implantation embryos.
format article
author Longqi Liu
Lizhi Leng
Chuanyu Liu
Changfu Lu
Yue Yuan
Liang Wu
Fei Gong
Shuoping Zhang
Xiaoyu Wei
Mingyue Wang
Lei Zhao
Liang Hu
Jian Wang
Huanming Yang
Shida Zhu
Fang Chen
Guangxiu Lu
Zhouchun Shang
Ge Lin
author_facet Longqi Liu
Lizhi Leng
Chuanyu Liu
Changfu Lu
Yue Yuan
Liang Wu
Fei Gong
Shuoping Zhang
Xiaoyu Wei
Mingyue Wang
Lei Zhao
Liang Hu
Jian Wang
Huanming Yang
Shida Zhu
Fang Chen
Guangxiu Lu
Zhouchun Shang
Ge Lin
author_sort Longqi Liu
title An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
title_short An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
title_full An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
title_fullStr An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
title_full_unstemmed An integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
title_sort integrated chromatin accessibility and transcriptome landscape of human pre-implantation embryos
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/f2377bee5d8a4fa08fc7cda946aac81e
work_keys_str_mv AT longqiliu anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT lizhileng anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT chuanyuliu anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT changfulu anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT yueyuan anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT liangwu anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT feigong anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT shuopingzhang anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT xiaoyuwei anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT mingyuewang anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT leizhao anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT lianghu anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT jianwang anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT huanmingyang anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT shidazhu anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT fangchen anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT guangxiulu anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT zhouchunshang anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT gelin anintegratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT longqiliu integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT lizhileng integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT chuanyuliu integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT changfulu integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT yueyuan integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT liangwu integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT feigong integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT shuopingzhang integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT xiaoyuwei integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT mingyuewang integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT leizhao integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT lianghu integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT jianwang integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT huanmingyang integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT shidazhu integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT fangchen integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT guangxiulu integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT zhouchunshang integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
AT gelin integratedchromatinaccessibilityandtranscriptomelandscapeofhumanpreimplantationembryos
_version_ 1718382123276042240

Ejemplares similares