THE PD-1/B7-H1-MEDIATED PRO-APOPTOTIC ACTIVITY OF DENDRITIC CELLS AS A POSSIBLE MECHANISM OF ANTIGEN-SPECIFIC RESPONSE FAILURE IN PATIENTS WITH PULMONARY TUBERCULOSIS
Abstract. The aim of present study was to investigate PD-1/B7-H1-mediated induction of T-cell apoptosis/ anergy, a suggested mechanism of reduced antigen-specific immune response against M. tuberculosis. We examined 76 patients with pulmonary tuberculosis (PT) who differed in levels of proliferative...
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Autores principales: | L. V. Sakhno, M. A. Tikhonova, T. V. Tyrinova, O. Yu. Leplina, S. D. Niconov, O. A. Zhdanov, A. A. Ostanin, E. R. Chernykh |
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Formato: | article |
Lenguaje: | RU |
Publicado: |
SPb RAACI
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/f243cd79275446b584f2c4dd21c1b600 |
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