A nanoconjugate Apaf-1 inhibitor protects mesothelial cells from cytokine-induced injury.

A nanoconjugate Apaf-1 inhibitor protects mesothelial cells from cytokine-induced injury.

<h4>Background</h4>Inflammation may lead to tissue injury. We have studied the modulation of inflammatory milieu-induced tissue injury, as exemplified by the mesothelium. Peritoneal dialysis is complicated by peritonitis episodes that cause loss of mesothelium. Proinflammatory cytokines...

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Bibliographic Details
Main Authors: Beatriz Santamaría, Alberto Benito-Martin, Alvaro Conrado Ucero, Luiz Stark Aroeira, Ana Reyero, María Jesús Vicent, Mar Orzáez, Angel Celdrán, Jaime Esteban, Rafael Selgas, Marta Ruíz-Ortega, Manuel López Cabrera, Jesús Egido, Enrique Pérez-Payá, Alberto Ortiz
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/f249c53c3d534c3399e5ebe849f6c00d
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