Smart pH-sensitive nanoassemblies with cleavable PEGylation for tumor targeted drug delivery

Smart pH-sensitive nanoassemblies with cleavable PEGylation for tumor targeted drug delivery

Abstract A new acidly sensitive PEGylated polyethylenimine linked by Schiff base (PEG-s-PEI) was designed to render pH-sensitive PEGylation nanoassemblies through multiple interactions with indomethacin and docetaxel (DTX). DTX nanoassemblies driven by PEG-s-PEI thus formulated exhibited an excellen...

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Bibliographic Details
Main Authors: Guanren Zhao, Ling Long, Lina Zhang, Mingli Peng, Ting Cui, Xiaoxun Wen, Xing Zhou, Lijun Sun, Ling Che
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/f24efb2af99c42939f556ba9d51a4be8
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