Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex

Chromosome conformation is a dynamic process, especially in brain. Here, Mitchell and colleagues devise a method they call NeuroDam that can prospectively tag chromosome conformation in the mouse brain in vivo, and longitudinally assess long range chromosome looping weeks and months later.

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Autores principales:	Amanda C. Mitchell, Behnam Javidfar, Lucy K. Bicks, Rachael Neve, Krassimira Garbett, Sharon S. Lander, Karoly Mirnics, Hirofumi Morishita, Marcelo A. Wood, Yan Jiang, Inna Gaisler-Salomon, Schahram Akbarian
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f253420b0f734648a73d3166c76192e2
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spelling	oai:doaj.org-article:f253420b0f734648a73d3166c76192e22021-12-02T15:35:20ZLongitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex10.1038/ncomms127432041-1723https://doaj.org/article/f253420b0f734648a73d3166c76192e22016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12743https://doaj.org/toc/2041-1723Chromosome conformation is a dynamic process, especially in brain. Here, Mitchell and colleagues devise a method they call NeuroDam that can prospectively tag chromosome conformation in the mouse brain in vivo, and longitudinally assess long range chromosome looping weeks and months later.Amanda C. MitchellBehnam JavidfarLucy K. BicksRachael NeveKrassimira GarbettSharon S. LanderKaroly MirnicsHirofumi MorishitaMarcelo A. WoodYan JiangInna Gaisler-SalomonSchahram AkbarianNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amanda C. Mitchell Behnam Javidfar Lucy K. Bicks Rachael Neve Krassimira Garbett Sharon S. Lander Karoly Mirnics Hirofumi Morishita Marcelo A. Wood Yan Jiang Inna Gaisler-Salomon Schahram Akbarian Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex
description	Chromosome conformation is a dynamic process, especially in brain. Here, Mitchell and colleagues devise a method they call NeuroDam that can prospectively tag chromosome conformation in the mouse brain in vivo, and longitudinally assess long range chromosome looping weeks and months later.
format	article
author	Amanda C. Mitchell Behnam Javidfar Lucy K. Bicks Rachael Neve Krassimira Garbett Sharon S. Lander Karoly Mirnics Hirofumi Morishita Marcelo A. Wood Yan Jiang Inna Gaisler-Salomon Schahram Akbarian
author_facet	Amanda C. Mitchell Behnam Javidfar Lucy K. Bicks Rachael Neve Krassimira Garbett Sharon S. Lander Karoly Mirnics Hirofumi Morishita Marcelo A. Wood Yan Jiang Inna Gaisler-Salomon Schahram Akbarian
author_sort	Amanda C. Mitchell
title	Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex
title_short	Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex
title_full	Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex
title_fullStr	Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex
title_full_unstemmed	Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex
title_sort	longitudinal assessment of neuronal 3d genomes in mouse prefrontal cortex
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f253420b0f734648a73d3166c76192e2
work_keys_str_mv	AT amandacmitchell longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT behnamjavidfar longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT lucykbicks longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT rachaelneve longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT krassimiragarbett longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT sharonslander longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT karolymirnics longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT hirofumimorishita longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT marceloawood longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT yanjiang longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT innagaislersalomon longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex AT schahramakbarian longitudinalassessmentofneuronal3dgenomesinmouseprefrontalcortex
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Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex

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