Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA

Genome recoding with quadruplet codons requires a +1-frameshift-suppressor tRNA able to insert an amino acid at quadruplet codons of interest. Here the authors identify the mechanisms resulting in +1 frameshifting and the steps of the elongation cycle in which it occurs.

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Detalles Bibliográficos
Autores principales:	Howard Gamper, Haixing Li, Isao Masuda, D. Miklos Robkis, Thomas Christian, Adam B. Conn, Gregor Blaha, E. James Petersson, Ruben L. Gonzalez, Ya-Ming Hou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f25e7830b887458f96ecdebbbd086160
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spelling	oai:doaj.org-article:f25e7830b887458f96ecdebbbd0861602021-12-02T15:22:39ZInsights into genome recoding from the mechanism of a classic +1-frameshifting tRNA10.1038/s41467-020-20373-z2041-1723https://doaj.org/article/f25e7830b887458f96ecdebbbd0861602021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20373-zhttps://doaj.org/toc/2041-1723Genome recoding with quadruplet codons requires a +1-frameshift-suppressor tRNA able to insert an amino acid at quadruplet codons of interest. Here the authors identify the mechanisms resulting in +1 frameshifting and the steps of the elongation cycle in which it occurs.Howard GamperHaixing LiIsao MasudaD. Miklos RobkisThomas ChristianAdam B. ConnGregor BlahaE. James PeterssonRuben L. GonzalezYa-Ming HouNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Howard Gamper Haixing Li Isao Masuda D. Miklos Robkis Thomas Christian Adam B. Conn Gregor Blaha E. James Petersson Ruben L. Gonzalez Ya-Ming Hou Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA
description	Genome recoding with quadruplet codons requires a +1-frameshift-suppressor tRNA able to insert an amino acid at quadruplet codons of interest. Here the authors identify the mechanisms resulting in +1 frameshifting and the steps of the elongation cycle in which it occurs.
format	article
author	Howard Gamper Haixing Li Isao Masuda D. Miklos Robkis Thomas Christian Adam B. Conn Gregor Blaha E. James Petersson Ruben L. Gonzalez Ya-Ming Hou
author_facet	Howard Gamper Haixing Li Isao Masuda D. Miklos Robkis Thomas Christian Adam B. Conn Gregor Blaha E. James Petersson Ruben L. Gonzalez Ya-Ming Hou
author_sort	Howard Gamper
title	Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA
title_short	Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA
title_full	Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA
title_fullStr	Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA
title_full_unstemmed	Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA
title_sort	insights into genome recoding from the mechanism of a classic +1-frameshifting trna
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f25e7830b887458f96ecdebbbd086160
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Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA

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