Prevalence and influencing factors of chronic obstructive pulmonary disease in rural areas of Moyu County, Xinjiang

Objective To analyze the status and influencing factors of chronic obstructive pulmonary disease (COPD) in rural areas of Moyu County, in the southern part of Xinjiang, and to provide scientific basis for early prevention and intervention strategies. Methods The baseline survey population in rural X...

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Autores principales: WANG Yide, LI Zheng, XU Dan, JING Jing, LIAO Chunyan, WANG Ting
Formato: article
Lenguaje:ZH
Publicado: Editorial Office of Journal of Third Military Medical University 2021
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Acceso en línea:https://doaj.org/article/f263ebc4f23f48aab0c69455ae14a875
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Sumario:Objective To analyze the status and influencing factors of chronic obstructive pulmonary disease (COPD) in rural areas of Moyu County, in the southern part of Xinjiang, and to provide scientific basis for early prevention and intervention strategies. Methods The baseline survey population in rural Xinjiang of the Natural Population Cohort Study in Northwest China was selected as the research object. A field survey was conducted from June to December 2018 in the rural areas of Moyu County, among the natural population aged 35 to 74, and the results of a questionnaire, physical examination and lung function measurement were collected. Finally, 3 249 valid samples were obtained. Stata 13.0 software was used for Chi-square test and trend Chi-square test. Univariate and multivariate binary logistic regression were adopted to analyze the correlation between related investigation factors and COPD. Results A total of 394 subjects (12.13%) were diagnosed with COPD. The prevalence of COPD was 12.59% (95% CI: 11.45%~13.83%) in subjects over 40 years old, it was increased with age (Chi-square trend=71.990, P < 0.001), and that of men was significantly higher than that of women (15.3% vs 10.1%, Chi-square=14.216, P < 0.001). After controlling confounding factors, multivariate logistic regression analysis showed that advanced age (50~ < 60 years old: OR=1.800, 95%CI: 1.203~2.694; 60~ < 70 years old: OR=3.035, 95%CI: 1.986~4.637; ≥70 years old: OR=5.602, 95%CI: 2.419~12.973), active smoking (OR=1.422, 95%CI: 1.077~1.877), use of traditional biofuels or coal (OR=2.258, 95%CI: 1.022~4.991), and a history of tuberculosis (OR=2.181, 95%CI: 1.291~3.682) were independent risk factors for local COPD. People with higher BMI (24.0~ < 28.0: OR=0.611, 95%CI: 0.449~0.830; ≥28.0: OR=0.470, 95%CI: 0.258~0.858) and using ventilation devices (OR=0.666, 95%CI: 0.473~0.937) had a lower risk of COPD. Conclusion The prevalence of COPD in rural areas of Moyu County is 12.13%, basically consistent with the domestic reports. In addition to the common risk factors like advanced age and smoking, the use of traditional biofuels or coal, lack of ventilation, and a history of tuberculosis are also closely associated with the risk of local COPD.