A gene expression signature of TREM2hi macrophages and γδ T cells predicts immunotherapy response

Most cancer patients do not respond to immune checkpoint therapies and the availability of predictive biomarkers is limited. Here the authors propose a signature enriched for genes of TREM2hi macrophages and γδ T cells to predict response to immunotherapy.

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Detalles Bibliográficos
Autores principales: Donghai Xiong, Yian Wang, Ming You
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f272e035b0804ec2a83b8daf7b11d346
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Sumario:Most cancer patients do not respond to immune checkpoint therapies and the availability of predictive biomarkers is limited. Here the authors propose a signature enriched for genes of TREM2hi macrophages and γδ T cells to predict response to immunotherapy.