Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines

During HIV infection, antiviral therapy can suppress viraemia to undetectable levels and hinder the progression towards AIDS; however the HIV-1 provirus can remain in long-lived CD4+ memory T cells. Here the authors show that intronic RNA from the HIV-1 provirus can induce type I interferon and infl...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sean Matthew McCauley, Kyusik Kim, Anetta Nowosielska, Ann Dauphin, Leonid Yurkovetskiy, William Edward Diehl, Jeremy Luban
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/f2742e3daba04908b834bf421e21448a
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!