Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations

Insight into the genetic influence on the immune response is important for the understanding of interindividual variability in human pathologies. Here, the authors generate transcriptome data from human blood monocytes stimulated with various immune stimuli and provide a time-resolved response eQTL...

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Autores principales:	Sarah Kim-Hellmuth, Matthias Bechheim, Benno Pütz, Pejman Mohammadi, Yohann Nédélec, Nicholas Giangreco, Jessica Becker, Vera Kaiser, Nadine Fricker, Esther Beier, Peter Boor, Stephane E. Castel, Markus M. Nöthen, Luis B. Barreiro, Joseph K. Pickrell, Bertram Müller-Myhsok, Tuuli Lappalainen, Johannes Schumacher, Veit Hornung
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f274c977e16349e182f563f89ede2112
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spelling	oai:doaj.org-article:f274c977e16349e182f563f89ede21122021-12-02T13:57:44ZGenetic regulatory effects modified by immune activation contribute to autoimmune disease associations10.1038/s41467-017-00366-12041-1723https://doaj.org/article/f274c977e16349e182f563f89ede21122017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00366-1https://doaj.org/toc/2041-1723Insight into the genetic influence on the immune response is important for the understanding of interindividual variability in human pathologies. Here, the authors generate transcriptome data from human blood monocytes stimulated with various immune stimuli and provide a time-resolved response eQTL map.Sarah Kim-HellmuthMatthias BechheimBenno PützPejman MohammadiYohann NédélecNicholas GiangrecoJessica BeckerVera KaiserNadine FrickerEsther BeierPeter BoorStephane E. CastelMarkus M. NöthenLuis B. BarreiroJoseph K. PickrellBertram Müller-MyhsokTuuli LappalainenJohannes SchumacherVeit HornungNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sarah Kim-Hellmuth Matthias Bechheim Benno Pütz Pejman Mohammadi Yohann Nédélec Nicholas Giangreco Jessica Becker Vera Kaiser Nadine Fricker Esther Beier Peter Boor Stephane E. Castel Markus M. Nöthen Luis B. Barreiro Joseph K. Pickrell Bertram Müller-Myhsok Tuuli Lappalainen Johannes Schumacher Veit Hornung Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
description	Insight into the genetic influence on the immune response is important for the understanding of interindividual variability in human pathologies. Here, the authors generate transcriptome data from human blood monocytes stimulated with various immune stimuli and provide a time-resolved response eQTL map.
format	article
author	Sarah Kim-Hellmuth Matthias Bechheim Benno Pütz Pejman Mohammadi Yohann Nédélec Nicholas Giangreco Jessica Becker Vera Kaiser Nadine Fricker Esther Beier Peter Boor Stephane E. Castel Markus M. Nöthen Luis B. Barreiro Joseph K. Pickrell Bertram Müller-Myhsok Tuuli Lappalainen Johannes Schumacher Veit Hornung
author_facet	Sarah Kim-Hellmuth Matthias Bechheim Benno Pütz Pejman Mohammadi Yohann Nédélec Nicholas Giangreco Jessica Becker Vera Kaiser Nadine Fricker Esther Beier Peter Boor Stephane E. Castel Markus M. Nöthen Luis B. Barreiro Joseph K. Pickrell Bertram Müller-Myhsok Tuuli Lappalainen Johannes Schumacher Veit Hornung
author_sort	Sarah Kim-Hellmuth
title	Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
title_short	Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
title_full	Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
title_fullStr	Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
title_full_unstemmed	Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
title_sort	genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f274c977e16349e182f563f89ede2112
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Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations

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