Managing blood pressure control in Asian patients: safety and efficacy of losartan

Tommy Tsang Cheung, Bernard Man Yung Cheung Division of Clinical Pharmacology and Therapeutics, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Abstract: Hypertension is common in Asian populations and is a major cause of cardiovascular diseases. The...

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Autores principales:	Cheung TT, Cheung BM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Hypertension Asians and Losartan Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/f27e2f75b1344766a1eeed2c86104713
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spelling	oai:doaj.org-article:f27e2f75b1344766a1eeed2c861047132021-12-02T02:45:55ZManaging blood pressure control in Asian patients: safety and efficacy of losartan1178-1998https://doaj.org/article/f27e2f75b1344766a1eeed2c861047132014-03-01T00:00:00Zhttps://www.dovepress.com/managing-blood-pressure-control-in-asian-patients-safety-and-efficacy--peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Tommy Tsang Cheung, Bernard Man Yung Cheung Division of Clinical Pharmacology and Therapeutics, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Abstract: Hypertension is common in Asian populations and is a major cause of cardiovascular diseases. The prevalence of hypertension is increasing in many Asian countries. The overall prevalence of hypertension in India and the People's Republic of China has been estimated to be 20.6% in men and 22.6% in women. However, the rates of detection, treatment, and control of hypertension remain low in Asia. This reflects a low level of literacy and education, as well as a low level of access to medical care. To overcome these obstacles, strategies targeted at education, promotion, and optimization of medical care, are crucial to achieve target blood pressure control. Angiotensin receptor blockers are one of the first-line treatments for essential hypertension because they confer better cardiovascular outcomes. Losartan has been widely evaluated for the management of hypertension. Although some studies suggested that the blood pressure-lowering effect of losartan is perhaps lower than for other angiotensin receptor blockers, losartan has been demonstrated to be beneficial in terms of renal protection in patients with diabetes, heart failure resulting from either systolic or diastolic dysfunction, and diuretic-induced hyperuricemia. However, most of these data were obtained from Caucasian populations. The efficacy and safety of losartan in Asian populations may be different because of genetic and ethnic variations. Therefore, the efficacy and safety of losartan in Asian patients with hypertension warrant further study. Keywords: hypertension, Asians, losartanCheung TTCheung BMDove Medical PressarticleHypertensionAsiansand LosartanGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 443-450 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Hypertension Asians and Losartan Geriatrics RC952-954.6
spellingShingle	Hypertension Asians and Losartan Geriatrics RC952-954.6 Cheung TT Cheung BM Managing blood pressure control in Asian patients: safety and efficacy of losartan
description	Tommy Tsang Cheung, Bernard Man Yung Cheung Division of Clinical Pharmacology and Therapeutics, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Abstract: Hypertension is common in Asian populations and is a major cause of cardiovascular diseases. The prevalence of hypertension is increasing in many Asian countries. The overall prevalence of hypertension in India and the People's Republic of China has been estimated to be 20.6% in men and 22.6% in women. However, the rates of detection, treatment, and control of hypertension remain low in Asia. This reflects a low level of literacy and education, as well as a low level of access to medical care. To overcome these obstacles, strategies targeted at education, promotion, and optimization of medical care, are crucial to achieve target blood pressure control. Angiotensin receptor blockers are one of the first-line treatments for essential hypertension because they confer better cardiovascular outcomes. Losartan has been widely evaluated for the management of hypertension. Although some studies suggested that the blood pressure-lowering effect of losartan is perhaps lower than for other angiotensin receptor blockers, losartan has been demonstrated to be beneficial in terms of renal protection in patients with diabetes, heart failure resulting from either systolic or diastolic dysfunction, and diuretic-induced hyperuricemia. However, most of these data were obtained from Caucasian populations. The efficacy and safety of losartan in Asian populations may be different because of genetic and ethnic variations. Therefore, the efficacy and safety of losartan in Asian patients with hypertension warrant further study. Keywords: hypertension, Asians, losartan
format	article
author	Cheung TT Cheung BM
author_facet	Cheung TT Cheung BM
author_sort	Cheung TT
title	Managing blood pressure control in Asian patients: safety and efficacy of losartan
title_short	Managing blood pressure control in Asian patients: safety and efficacy of losartan
title_full	Managing blood pressure control in Asian patients: safety and efficacy of losartan
title_fullStr	Managing blood pressure control in Asian patients: safety and efficacy of losartan
title_full_unstemmed	Managing blood pressure control in Asian patients: safety and efficacy of losartan
title_sort	managing blood pressure control in asian patients: safety and efficacy of losartan
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/f27e2f75b1344766a1eeed2c86104713
work_keys_str_mv	AT cheungtt managingbloodpressurecontrolinasianpatientssafetyandefficacyoflosartan AT cheungbm managingbloodpressurecontrolinasianpatientssafetyandefficacyoflosartan
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Managing blood pressure control in Asian patients: safety and efficacy of losartan

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