The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Only very few enzymes are known to catalyze protein histidine methylation. Here, the authors show that METTL9 is responsible for most 1-methylhistidine modifications in mouse and human proteomes, and characterize METTL9′s substrate specificity and potential cellular functions.
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
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| Accès en ligne: | https://doaj.org/article/f285ea6c5c6e4717b078c180ed9b6cd5 |
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