<italic toggle="yes">Toxoplasma</italic> Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion

<italic toggle="yes">Toxoplasma</italic> Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion

ABSTRACT The lysosome-like vacuolar compartment (VAC) is a major site of proteolysis in the intracellular parasite Toxoplasma gondii. Previous studies have shown that genetic ablation of a VAC-residing cysteine protease, cathepsin protease L (CPL), resulted in the accumulation of undigested protein...

Full description

Saved in:
Bibliographic Details
Main Authors: Christian McDonald, David Smith, Manlio Di Cristina, Geetha Kannan, Zhicheng Dou, Vern B. Carruthers
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
Toxoplasma gondii
autophagy
cathepsin
lysosome
proteases
Microbiology
QR1-502
Online Access:https://doaj.org/article/f28ca7b56c8f483ca29aa45225b73bdc
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items